Patents by Inventor Balamayooran Theivanthiran

Balamayooran Theivanthiran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUMOR-INTRINSIC NLRP3 INFLAMMASOME SIGNALING PATHWAY AS A GENETIC AND FUNCTIONAL BIOMARKER FOR IMMUNOTHERAPY RESPONSE
    Publication number: 20230152324
    Abstract: The present disclosure describes methods and markers in the NLRP3-HSP70 axis useful for making treatment decisions regarding cancer.
    Type: Application
    Filed: November 14, 2022
    Publication date: May 18, 2023
    Inventors: Brent A. Hanks, Balamayooran Theivanthiran
  • Predictive biomarkers for cancer immunotherapy and methods of using same
    Patent number: 11643691
    Abstract: The present disclosure provides methods of detecting a wnt-?-catenin-mediated cancer and an immunotherapy resistant cancer by detecting the presence of an associated biomarker. Further, methods of threating the wnt-?-catenin-mediated cancer or immunotherapy resistant cancer are provided.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: May 9, 2023
    Assignee: Duke University
    Inventors: Brent Hanks, Nicholas Devito, Balamayooran Theivanthiran, Fei Zhao
  • COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF ANTI-PD-1 ANTIBODY IMMUNOTHERAPY
    Publication number: 20210077582
    Abstract: The present disclosure provides, in part, compositions and methods of increasing the efficacy of anti-PD-1/PD-L1 antibody immunotherapy in a subject. The compositions and methods comprise an NLRP3 inhibitor used in combination with a PD-1 or PD-L1 inhibitor for the treatment of cancer.
    Type: Application
    Filed: September 14, 2020
    Publication date: March 18, 2021
    Applicant: Duke University
    Inventors: Brent Hanks, Balamayooran Theivanthiran
  • PREDICTIVE BIOMARKERS FOR CANCER IMMUNOTHERAPY AND METHODS OF USING SAME
    Publication number: 20190316208
    Abstract: The present disclosure provides methods of detecting a wnt-?-catenin-mediated cancer and an immunotherapy resistant cancer by detecting the presence of an associated biomarker. Further, methods of threating the wnt-?-catenin-mediated cancer or immunotherapy resistant cancer are provided.
    Type: Application
    Filed: April 15, 2019
    Publication date: October 17, 2019
    Inventors: Brent Hanks, Nicholas Devito, Balamayooran Theivanthiran, Fei Zhao