Patents by Inventor Balamurali Ambati

Balamurali Ambati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF MYOPIA
    Publication number: 20240122974
    Abstract: The present invention provides methods of treating myopia comprising administering composition comprising a cop-per-containing agent to an eye of a subject in need thereof.
    Type: Application
    Filed: February 11, 2022
    Publication date: April 18, 2024
    Applicant: University of Utah Research Foundation
    Inventors: Balamurali Ambati, Sarah A. Molokhia
  • TREATMENT OF ASTIGMATISM
    Publication number: 20240091255
    Abstract: The present invention provides methods of treating corneal astigmatism comprising administering composition comprising a copper-containing agent to an eye of a subject in need thereof.
    Type: Application
    Filed: January 28, 2022
    Publication date: March 21, 2024
    Inventors: Balamurali Ambati, Sarah A. Molokhia
  • DIVALENT METAL-CONTAINING BIOMATERIALS AND METHODS OF USE
    Publication number: 20230145406
    Abstract: Biocompatible materials including a biodegradable hydrogel and an active agent including a divalent metal salt are provided. Methods of making the biocompatible materials and methods of use, for example for treating an eye disease or disorder, such as keratoconus, are also provided.
    Type: Application
    Filed: November 10, 2022
    Publication date: May 11, 2023
    Applicant: University of Oregon
    Inventors: Balamurali Ambati, Sangeetha Ravi Kumar, Kaleb Roach
  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20180141995
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: September 19, 2016
    Publication date: May 24, 2018
    Applicants: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • SCHLEMM'S CANAL STENT-SIEVE
    Publication number: 20160331588
    Abstract: An ocular stent device (100) can include an elongate arcuate body portion (102) configured in size and shape to be inserted into the Schlemm's canal. The body portion (102) can be inserted along an arc of at least 100 degrees of the Schlemm's canal. The body portion (102) can include a plurality of through-holes (104) adapted to direct flow of aqueous humor from a trabecular meshwork to episcleral collector channels of the eye.
    Type: Application
    Filed: January 14, 2015
    Publication date: November 17, 2016
    Inventors: Balamurali Ambati, Alan Crandall, Bruce K. Gale, Christopher Lambert
  • Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
    Patent number: 9447166
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: September 20, 2016
    Assignees: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20140329888
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: March 31, 2014
    Publication date: November 6, 2014
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors
    Publication number: 20130130980
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: July 2, 2012
    Publication date: May 23, 2013
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
    Patent number: 8211864
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: July 3, 2012
    Assignees: Medical College of Georgia Research Institute, University of Utah Research Foundation
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin
  • Compositions and Methods for the Intracellular Disruption of Vegf and Vegfr-2 By Intraceptors
    Publication number: 20080318857
    Abstract: The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
    Type: Application
    Filed: January 26, 2006
    Publication date: December 25, 2008
    Inventors: Balamurali Ambati, Nirbhai Singh, Shivan Amin