Patents by Inventor Balamurugan Arumugam

Balamurugan Arumugam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion Fragment Chimeric Antigen Receptors and Uses Thereof
    Publication number: 20210252068
    Abstract: Disclosed herein are fusion fragment chimeric antigen receptors (FF-CARs), engineered cells expressing FF-CARs, and methods of using thereof to treat, reduce, or inhibit infections by enveloped viruses in subjects.
    Type: Application
    Filed: June 13, 2019
    Publication date: August 19, 2021
    Inventors: Otto O. Yang, Ph.D., Balamurugan Arumugam
  • Recombinant human progenitor cells, engineered human thymocytes, and engineered human T cells
    Patent number: 9228007
    Abstract: Disclosed herein are recombinant human progenitor cells, engineered human thymocytes, and engineered human T cells. The recombinant human progenitor cells are made by transducing a human hematopoietic stem cell with a vector having a nucleic acid molecule which encodes a human T cell receptor specific to a virus, such as Human Immunodeficiency Virus, or an epitope thereof. The recombinant human progenitor cells differentiate and mature into the engineered human thymocytes and the engineered human T cells. Also disclosed herein are methods of inhibiting, reducing or treating a viral infection in a subject, such as a human subject, which comprises administering recombinant human progenitor cells, engineered human thymocytes, and/or engineered human T cells to the subject.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: January 5, 2016
    Assignee: The Regents of the University of California
    Inventors: Scott G. Kitchen, Jerome A. Zack, Otto O. Yang, Michael S. Bennett, Balamurugan Arumugam