Patents by Inventor Balasingam Radhakrishan

Balasingam Radhakrishan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
    Patent number: 7196059
    Abstract: Pharmaceutical compositions that include insulin, an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component or a bile salt component without a fatty acid component are described. The insulin drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component, when together, can be present in a weight-to-weight ratio of between 1:15 and 15:1. Methods of treating an insulin deficiency in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.
    Type: Grant
    Filed: March 5, 2003
    Date of Patent: March 27, 2007
    Assignee: Biocon Limited
    Inventors: Richard Soltero, Balasingam Radhakrishan, Nnochiri N. Ekwuribe, Bruce Rehlaender, Anthony Hickey, Li Li Bovet
  • Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
    Patent number: 6867183
    Abstract: Pharmaceutical compositions that include an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The insulin drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating an insulin deficiency in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: March 15, 2005
    Assignee: Nobex Corporation
    Inventors: Richard Soltero, Balasingam Radhakrishan, Nnochiri N. Ekwuribe, Bruce Rehlaender, Anthony Hickey, Li Li Bovet