Patents by Inventor Baldassarre D. Stea

Baldassarre D. Stea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL MRNA BASED PROGNOSTIC INDEX DERIVED FROM DIFFERENTIAL EXPRESSION ANALYSIS IMPROVES OVERALL SURVIVAL ESTIMATES IN GLIOBLASTOMA
    Publication number: 20210317537
    Abstract: The present invention relates to diagnostic assays useful in classification of patients for selection of cancer therapy, and relates to a method of using a select family member of the Wnt signaling pathway (WIF1), an important component of the insulin-like growth factor pathway (IGFBP3), and other signaling factors (e.g., NGFR, IBSP, and HISTLH3G and COL1A2) as prognostic markers and potential therapeutic targets for patients with Glioblastoma Multiforme (GBM). In particular, the present invention is a novel GBM Prognostic Index (GPI) that predicts overall survival (OS) in GBM patients treated with the current standard of care.
    Type: Application
    Filed: May 14, 2021
    Publication date: October 14, 2021
    Inventors: Eric Weterings, Baldassarre D. Stea, Daruka Mahadevan, Christopher Michael Morrison, Michael F. Hammer