Patents by Inventor Balram Ghosh

Balram Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treatment of bronchial asthma
    Patent number: 8519154
    Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: August 27, 2013
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sibabrata Mukhopadhyay, Mumu Chakraborty, Tulika Mukherjee, Arun Bandyopadhyay, Dipak Kar, Tanima Banerjee, Aditya Konar, Debaprasad Jana, Siddhartha Roy, Santu Bandyopadhyay, Balram Ghosh, Mabalirajan Ulaganathan, Rakesh Kamal Johri, Subhash Chander Sharma, Gurdarshan Singh, Bholanath Paul, Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety
  • Primers for amplifying and detecting the beta 2 adrenergic receptor gene
    Patent number: 8268983
    Abstract: Present invention relates to a method for predicting an individual's bronchodilatory response to a ? agonist. Present invention particularly relates to the detection of specific allelic variants of the ?2AR gene and their use as pharmacogenetic markers towards response to ? agonist.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: September 18, 2012
    Assignees: Council of Scientific & Industrial Research, Piramal Life Sciences Limited
    Inventors: Ritushree Kukreti, Pallav Bhatnagar, Chandrika Rao, Balram Ghosh, Samir Kumar Brahmachari, Randeep Guleria, Chinmoyee Das
  • METHOD FOR TREATMENT OF BRONCHIAL ASTHMA
    Publication number: 20120202868
    Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.
    Type: Application
    Filed: February 3, 2012
    Publication date: August 9, 2012
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sibabrata MUKHOPADHYAY, Mumu CHAKRABORTY, Tulika MUKHERJEE, Arun BANDYOPADHYAY, Dipak KAR, Tanima BANERJEE, Aditya KONAR, Debaprasad JANA, Siddhartha ROY, Santu BANDYOPADHYAY, Balram GHOSH, Mabalirajan ULAGANATHAN, Rakesh Kamal JOHRI, Subhash Chander SHARMA, Gurdarshan SINGH, Bholanath PAUL, Vasanta Madhava Sharma GANGAVARAM, Jhillu Singh YADAV, Radha Krishna PALAKODETY
  • Method of detecting and predicting bronchodilatory response to beta agonist
    Patent number: 8093004
    Abstract: Present invention relates to a method for predicting an individual's bronchodilatory response to a ? agonist. Present invention particularly relates to the detection of specific allelic variants of the ?2AR gene and their use as pharmacogenetic markers towards response to ? agonist.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: January 10, 2012
    Assignees: Council of Scientific & Industrial Research, Piramal Life Sciences Limited
    Inventors: Ritushree Kukreti, Pallav Bhatnagar, Chandrika Rao, Balram Ghosh, Samir Kumar Brahmachari, Randeep Guleria, Chinmoyee Das
  • Gene variants of signal transducer and activator of transcription-6 (STAT 6) variants and process of detection the same
    Patent number: 7671182
    Abstract: The present invention relates to allelic variants of the human Signal Transducer and Activator of Transcription-6 (STAT6) gene and provides primers and methods suitable for the detection of these allelic variants for applications such as molecular diagnosis, prediction of an individual's disease susceptibility, and /or the genetic analysis of the STAT6 gene in a population. Specifically, the invention provides a method for detection of predisposition to atopic disorders/other immunological disorders such as, autoimmune disorders, inflammatory disorders, fibrosis, etc. where STAT6 plays an important role by screening for human Signal Transducer and Activator of Transcription-6 (STAT 6) gene variants.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: March 2, 2010
    Assignee: Council of Scientific & Industrial Research
    Inventors: Balram Ghosh, Rana Nagarkatti, Chandrika B. Rao
  • Method of detecting and predicting bronchodilatory response to beta agonist
    Publication number: 20090047682
    Abstract: Present invention relates to a method for predicting an individual's bronchodilatory response to a ? agonist. Present invention particularly relates to the detection of specific allelic variants of the ?2AR gene and their use as pharmacogenetic markers towards response to ? agonist.
    Type: Application
    Filed: September 8, 2008
    Publication date: February 19, 2009
    Inventors: Ritushree Kukreti, Pallav Bhatnagar, Chandrika Rao, Balram Ghosh, Samir Kumar Brahmachari, Randeep Guleria, Chinmoyee Das
  • Method of detecting and predicting bronchodilatory response to beta agonist
    Publication number: 20050255479
    Abstract: Present invention relates to a method for predicting an individual's bronchodilatory response to a ? agonist. Present invention particularly relates to the detection of specific allelic variants of the ?2AR gene and their use as pharmacogenetic markers towards response to ? agonist.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 17, 2005
    Inventors: Ritushree Kukreti, Pallav Bhatnagar, Chandrika Rao, Balram Ghosh, Samir Brahmachari, Randeep Guleria, Chinmoyee Das
  • Gene variants of signal transducer and activator of transcription-6 (STAT 6) variants and process of detection the same
    Publication number: 20050136418
    Abstract: The present invention relates to allelic variants of the human Signal Transducer and Activator of Transcription-6 (STAT6) gene and provides primers and methods suitable for the detection of these allelic variants for applications such as molecular diagnosis, prediction of an individual's disease susceptibility, and /or the genetic analysis of the STAT6 gene in a population. Specifically, the invention provides a method for detection of predisposition to atopic disorders/other immunological disorders such as, autoimmune disorders, inflammatory disorders, fibrosis, etc. where STAT6 plays an important role by screening for human Signal Transducer and Activator of Transcription-6 (STAT 6) gene variants.
    Type: Application
    Filed: March 30, 2004
    Publication date: June 23, 2005
    Inventors: Balram Ghosh, Rana Nagarkatti, Chandrika Rao