Patents by Inventor Bao-Ping Zhao

Bao-Ping Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,6 Naphthridines useful as inhibitors of SYK kinase
    Patent number: 7705151
    Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: April 27, 2010
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Scott E. Jakes, Joachim Heider, Mark A. Bobko, Renee L. Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-ping Zhao
  • 1,6 naphthyridines useful as inhibitors of SYK kinase
    Patent number: 7678911
    Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: January 15, 2008
    Date of Patent: March 16, 2010
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Scott E. Jakes, Joachim Heider, Mark A. Bobko, Renee L. Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-ping Zhao
  • Hetero isonipecotic modulators of vanilloid VR1 receptor
    Patent number: 7622579
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: November 24, 2009
    Assignee: Janssen Pharmaceutica NV
    Inventors: Micheal D. Gaul, Bao-Ping Zhao, Daniel A. Hutta
  • 1,6 NAPHTHRIDINES USEFUL AS INHIBITORS OF SYK KINASE
    Publication number: 20090171089
    Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Application
    Filed: March 6, 2009
    Publication date: July 2, 2009
    Applicant: BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.
    Inventors: Charles L. CYWIN, Scott E. JAKES, Joachim HEIDER, Mark A. BOBKO, Renee L. DES JARLAIS, Mark PLAYER, James RINKER, Michael WINTERS, Bao-ping ZHAO
  • 4-amino-quinazolines
    Patent number: 7547702
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein 1bIX antagonists.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: June 16, 2009
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Werner Mederski, Maria Devant, legal representative, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R. Player, Edward Jaegar, Richard Soll, Ralf Devant
  • Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor
    Publication number: 20090069305
    Abstract: The present invention relates to substituted nitrogen-containing heteroaryl derivatives, pharmaceutical compositions containing them, and methods of using any of these derivatives and compositions for H4 receptor activity modulation and the treatment of states mediated by histamine H4 receptor activity.
    Type: Application
    Filed: September 11, 2008
    Publication date: March 12, 2009
    Inventors: Michael D. Gaul, Bao-Ping Zhao, Xizhen Zhu
  • 1,6 NAPHTHYRIDINES USEFUL AS INHIBITORS OF SYK KINASE
    Publication number: 20080114024
    Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Application
    Filed: January 15, 2008
    Publication date: May 15, 2008
    Inventors: Charles CYWIN, Scott Jakes, Joachim Heider, Mark Bobko, Renee Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-ping Zhao
  • 1,6 Naphthyridines useful as inhibitors of SYK kinase
    Patent number: 7321041
    Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: January 22, 2008
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Scott E. Jakes, Joachim Heider, Mark A. Bobko, Renee L. Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-ping Zhao
  • 4-Amino-quinazolines
    Publication number: 20070293667
    Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: December 14, 2005
    Publication date: December 20, 2007
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • AMINOQUINOLINE AND AMINOQUINAZOLINE KINASE MODULATORS
    Publication number: 20070004763
    Abstract: The invention is directed to aminoquinoline and aminoquinazoline compounds of Formula I: where R1, R2, R3, B, Z, Q, p, q and X are as defined herein, the use of such compounds as protein tyrosine kinase modulators, particularly inhibitors of FLT3 and/or TrkB, the use of such compounds to reduce or inhibit kinase activity of FLT3 and/or TrkB in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to FLT3 and/or TrkB. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as cancers and other cell proliferative disorders.
    Type: Application
    Filed: June 6, 2006
    Publication date: January 4, 2007
    Inventors: Nand Baindur, Michael Gaul, Kevin Kreutter, Christian Baumann, Alexander Kim, Guozhang Xu, Bao-Ping Zhao
  • Quinazolinones
    Patent number: 7060706
    Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, n and m have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: June 13, 2006
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, Guido Melzer, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Richard Soll
  • 4-Amino-quinazolines
    Publication number: 20060019974
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: September 17, 2001
    Publication date: January 26, 2006
    Inventors: Werner Mederski, Ralf Devant, Maria Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • Hetero isonipecotic modulators of vanilloid VR1 receptor
    Publication number: 20050288281
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 29, 2005
    Inventors: Michael Gaul, Bao-Ping Zhao, Daniel Hutta
  • 4-amino-quinazolines
    Publication number: 20040044204
    Abstract: Quinazolines of the formula I, in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: March 20, 2003
    Publication date: March 4, 2004
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R Player, Edward Jaeger, Richard Soll
  • 1,6 Naphthyridines useful as inhibitors of SYK kinase
    Publication number: 20030229090
    Abstract: Disclosed are compounds of formula (I): 1
    Type: Application
    Filed: April 15, 2003
    Publication date: December 11, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Scott E. Jakes, Joachim Heider, Mark A. Bobko, Renee L. Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-Ping Zhao
  • 1,6 naphthyridines useful as inhibitors of SYK kinase
    Publication number: 20030158195
    Abstract: Disclosed are compounds of formula (I): 1
    Type: Application
    Filed: December 21, 2001
    Publication date: August 21, 2003
    Inventors: Charles L. Cywin, Scott E. Jakes, Joachim Heider, Mark A. Bobko, Renee L. Des Jarlais, Mark Player, James Rinker, Michael Winters, Bao-Ping Zhao