Patents by Inventor Bao-Xi Qu

Bao-Xi Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amyloid ? gene vaccines
    Patent number: 7479550
    Abstract: The invention generally concerns compositions and methods for genetic vaccination with amyloid beta (A?) protein. Such vaccines may provide effective treatment for neurodegenerative disease such as Alzheimer's disease. Vaccination methods are can be used to induce a Th2 type immune response directed to A?. This immune response id shown to substantially reduce A? concentration and A? plaque size in an Alzheimer's model system.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: January 20, 2009
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Roger N. Rosenberg, Stephen A. Johnston, Bao-Xi Qu
  • Rationally designed and chemically synthesized promoter for genetic vaccine and gene therapy
    Patent number: 7312202
    Abstract: The present invention relates to chemically synthesized promoters that circumvent the disadvantages of the universal CMV promoter/enhancer elements. The promoter may be used in a variety of applications, particularly in genetic immunization. The chemically synthesized promoter overcomes the common problems of the CMV promoter element such as: low transgene expression levels, transient expression, and the large amount of plasmid DNA needed for intramuscular injection in subjects.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: December 25, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventors: Stephen Johnston, Bao-Xi Qu
  • Amyloid beta gene vaccines
    Publication number: 20070280953
    Abstract: The invention generally concerns compositions and methods for genetic vaccination with amyloid beta (A?) protein. Such vaccines may provide effective treatment for neurodegenerative disease such as Alzheimer's disease. Vaccination methods are can be used to induce a Th2 type immune response directed to A?. This immune response id shown to substantially reduce A? concentration and A? plaque size in an Alzheimer's model system.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 6, 2007
    Inventors: Roger N. Rosenberg, Stephen A. Johnston, Bao-Xi Qu
  • Rationally designed and chemically synthesized promoter for genetic vaccine and gene therapy
    Publication number: 20040171573
    Abstract: The present invention relates to chemically synthesized promoters that circumvent the disadvantages of the universal CMV promoter/enhancer elements. The promoter may be used in a variety of applications, particularly in genetic immunization. The chemically synthesized promoter overcomes the common problems of the CMV promoter element such as: low transgene expression levels, transient expression, and the large amount of plasmid DNA needed for intramuscular injection in subjects.
    Type: Application
    Filed: February 18, 2004
    Publication date: September 2, 2004
    Applicant: Board of Regents, The University of Texas System
    Inventors: Stephen Johnston, Bao-Xi Qu