Publication number: 20240228532
Abstract: Provided is, inter alia, a method, comprising: complexing a peptide-comprising surfactant (PEPS) to a rare earth element (REE) cation in a solution so as to form a PEPS-REE complex, the PEPS comprising a REE-binding region that preferentially binds to one or more REEs; and optionally recovering the REE cation from an air-liquid interface. Also provided is a composition, comprising: a complex comprising (i) a peptide-comprising surfactant (PEPS), the PEPS comprising at least one lanthanide binding tag (LBT), the at least one LBT comprising one or more residues arranged in a binding region that coordinates with an REE cation so as to form a PEPS-REE cation complex, and (ii) an REE cation, the REE cation of the complex coordinated with the binding region of the PEPS. Further provided is a method, comprising application of at least one of molecular dynamics, artificial intelligence, and a genetic algorithm to design a PEPS that comprises an LBT and preferentially binds one REE over at least one other REE.
Type:
Application
Filed:
August 11, 2023
Publication date:
July 11, 2024
Inventors:
Kathleen J. Stebe, Daeyeon Lee, Ravi Radhakrishnan, César de la Fuente-Nunez, Ivan Julian Dmochowski, E. James Petersson, Jason G. Marmorstein, Stephen Crane, Eshe Jael Hummingbird, Yiming Wang, Elizabeth J. Biddinger, Charles Maldarelli, Robert J. Messinger, Raymond S. Tu, Luis Ortuno Macias, Surabh S. KT, Mark L. Schlossman, Bikash Sapkota, Pan Sun, Monica Olvera de la Cruz, Felipe Jiménez-Ángeles, Baofu Qiao
