Abstract: Provided herein is a method of suppressing osteoclast differentiation or function and/or bone resorption or destruction in a subject in need thereof and compositions therefore. In one embodiment, the method includes increasing the amount, expression, or activity of Foxo3 isoform 2 in the subject.

Abstract: The invention provides an LED panel light and a frame component. The frame component includes a frame and a moving plate, wherein the moving plate is assembled at the inner side of the frame movably, an extrusion space is formed between the opposite faces of the moving plate and the frame, an expansion piece is assembled in the extrusion space, the moving plate is close to a light guide plate located at the inner side of the moving plate due to an extrusion counterforce of the expansion piece, and the side face of the moving plate in the face of the light guide plate is provided with a light source assembling area for assembling a light source component.

Abstract: The invention provides an LED panel light and a frame component. The frame component includes a frame and a moving plate, wherein the moving plate is assembled at the inner side of the frame movably, an extrusion space is formed between the opposite faces of the moving plate and the frame, an expansion piece is assembled in the extrusion space, the moving plate is close to a light guide plate located at the inner side of the moving plate due to an extrusion counterforce of the expansion piece, and the side face of the moving plate in the face of the light guide plate is provided with a light source assembling area for assembling a light source component.