Patents by Inventor Baolei Zhang

Baolei Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid form of dihydropyrimidine compound and preparation method therefor and use thereof
    Patent number: 11434235
    Abstract: Disclosed are a solid form of (E)-3-((R)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)acrylic acid, a preparation method therefor, a pharmaceutical composition comprising same, and the use thereof in the preparation of drugs for preventing or treating viral diseases.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: September 6, 2022
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Tianming Wang, Chengxi Yang, Jiaqiang Cai, Wei Liu, Baolei Zhang, Qiang Tian, Shuai Song, Hao Hu, Weibiao Han, Youqiang Li, Xing Chen, Lichun Wang, Jingyi Wang
  • Phosphonamide ester compound, salt thereof, related crystal form thereof, preparation method therefor and use thereof
    Patent number: 11186599
    Abstract: The present invention relates to compounds represented by formula (I) and formula (II) and a chiral synthesis and chiral isolation method therefor, further relating to a salt and crystal form of the compound represented by formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the preparation of a medicament used for the treatment of a viral infectious disease such as hepatitis B.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: November 30, 2021
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Qiang Tian, Tianming Wang, Wei Liu, Baolei Zhang, Mingliang Zhao, Yufeng Liang, Jiaqiang Cai, Lichun Wang, Jingyi Wang
  • PHOSPHONAMIDE ESTER COMPOUND, SALT THEREOF, RELATED CRYSTAL FORM THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20210179647
    Abstract: The present invention relates to compounds represented by formula (I) and formula (II) and a chiral synthesis and chiral isolation method therefor, further relating to a salt and crystal form of the compound represented by formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the preparation of a medicament used for the treatment of a viral infectious disease such as hepatitis B.
    Type: Application
    Filed: June 3, 2019
    Publication date: June 17, 2021
    Applicant: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
    Inventors: Qiang TIAN, Tianming WANG, Wei LIU, Baolei ZHANG, Mingliang ZHAO, Yufeng LIANG, Jiaqiang CAI, Lichun WANG, Jingyi WANG
  • SOLID FORM OF DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20210024514
    Abstract: Disclosed are a solid form of (E)-3-((R)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)acrylic acid, a preparation method therefor, a pharmaceutical composition comprising same, and the use thereof in the preparation of drugs for preventing or treating viral diseases.
    Type: Application
    Filed: May 6, 2019
    Publication date: January 28, 2021
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: TIANMING WANG, CHENGXI YANG, JIAQIANG CAI, WEI LIU, BAOLEI ZHANG, QIANG TIAN, SHUAI SONG, HAO HU, WEIBIAO HAN, YOUQIANG LI, XING CHEN, LICHUN WANG, JINGYI WANG
  • Dihydropteridinone derivatives, preparation process and pharmaceutical use thereof
    Patent number: 8691822
    Abstract: Dihydroperidinone derivatives, preparation process and pharmaceutical use thereof are disclosed. Specially, new dihydroperidinone derivatives represented by general formula (I), wherein each substituent of the general formula (I) is defined as in the description, their preparation process, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors are disclosed.
    Type: Grant
    Filed: September 14, 2010
    Date of Patent: April 8, 2014
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Peng Cho Tang, Nong Zhang, Baolei Zhang, Weimin Wang, Hao Zheng, Lin Wu
  • DIHYDROPTERIDINONE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF
    Publication number: 20120184543
    Abstract: Dihydroperidinone derivatives, preparation process and pharmaceutical use thereof are disclosed. Specially, new dihydroperidinone derivatives represented by general formula (I), wherein each substituent of the general formula (I) is defined as in the description, their preparation process, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors are disclosed.
    Type: Application
    Filed: September 14, 2010
    Publication date: July 19, 2012
    Applicants: SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD., JIANGSU HENGRUI MEDICINE CO., LTD.
    Inventors: Peng Cho Tang, Nong Zhang, Baolei Zhang, Weimin Wang, Hao Zheng, Lin Wu