Abstract: Embodiments of the present specification provide a data migration method based on a heterogeneous memory, the heterogeneous memory comprising a high-speed memory and a low-speed memory. The method comprises: determining access frequency information of memory pages by monitoring a memory access operation for the heterogeneous memory; and migrating, under a first condition, cold data in the high-speed memory to the low-speed memory, the cold data being determined based on the access frequency information.

Abstract: A horn mounting structure, includes: a shell, a sound hole is formed at a side surface of the shell; a mounting groove formed inside the shell, and the sound hole is communicated with the mounting groove; a holder, the holder is bonded in the mounting groove through a sealant, and a front sound chamber is formed at one side of the holder facing to the sound hole, and a horn, and the horn is bonded to one side of the holder facing away from the shell through the sealant.

Abstract: The present invention provides a simple process of preparing avibactam. Piperidine-5-one-2S-carboxylate II as the raw material is subjected to condensation reaction with O-protecting hydroxylamine hydrochloride; the resulting compound is subjected to reduction and chiral resolution to obtain 5R-substituted oxyaminopiperidine-2S-carboxylic acid V in a basic condition; then, the compound of formula V is subjected to urea cyclization, acyl chlorination, and amidation with phosgene, solid phosgene, or diphosgene in a “one-pot” process, and then subjected to deprotection, sulfation, and tetrabutylammonium salt formation reaction to obtain (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxy}sulfonyl tetra-n-butyl ammonium salt VII, and finally, the compound of formula VII is subjected to ion exchange to obtain avibactam I.

Abstract: The present invention provides a simple process of preparing avibactam. Piperidine-5-one-2S-carboxylate II as the raw material is subjected to condensation reaction with O-protecting hydroxylamine hydrochloride; the resulting compound is subjected to reduction and chiral resolution to obtain 5R-substituted oxyaminopiperidine-2S-carboxylic acid V in a basic condition; then, the compound of formula V is subjected to urea cyclization, acyl chlorination, and amidation with phosgene, solid phosgene, or diphosgene in a “one-pot” process, and then subjected to deprotection, sulfation, and tetrabutylammonium salt formation reaction to obtain (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxy}sulfonyl tetra-n-butyl ammonium salt VII, and finally, the compound of formula VII is subjected to ion exchange to obtain avibactam I.

Abstract: The present application relates to methods of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or its derivatives in an environment-friendly way. The method uses L-glutamic acid as a starting material, which is first subjected to esterification reaction in the presence of an acidic reagent, and then reacted successively with 2-haloacetate and N-protecting agent, or with N-protecting agent and 2-haloacetate under a basic condition to obtain compound IV; then, the obtained compound IV is subjected to intramolecular condensation into a ring under the action of a strong base to obtain N-protecting group piperidine-5-one-2S-carboxylate (V).

Abstract: The present application relates to methods of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or its derivatives in an environment-friendly way. The method uses L-glutamic acid as a starting material, which is first subjected to esterification reaction in the presence of an acidic reagent, and then reacted successively with 2-haloacetate and N-protecting agent, or with N-protecting agent and 2-haloacetate under a basic condition to obtain compound IV; then, the obtained compound IV is subjected to intramolecular condensation into a ring under the action of a strong base to obtain N-protecting group piperidine-5-one-2S-carboxylate (V).

Abstract: A horn mounting structure, includes: a shell, a sound hole is formed at a side surface of the shell; a mounting groove formed inside the shell, and the sound hole is communicated with the mounting groove; a holder, the holder is bonded in the mounting groove through a sealant, and a front sound chamber is formed at one side of the holder facing to the sound hole, and a horn, and the horn is bonded to one side of the holder facing away from the shell through the sealant.

Abstract: An information retrieval method, an electronic device and a storage medium are provided. The method comprises: sending at least one keyword in chatting contents in an input box of an instant messenger to a server, when it is detected that the chatting contents need to be sent to a communication counterpart; receiving, from the server based on the at least one keyword, retrieved contents and at least one category in which the retrieved contents are categorically stored in the server; and categorically displaying the retrieved contents in a current interface, in accordance with the at least one category.

Abstract: The disclosure relates to a method and device for displaying a floating window. The method includes monitoring an amount of floating windows that are created on a desktop for respective ones of a plurality of applications; determining that there is more than one of the plurality of applications for which a floating window is created on the desktop; forbidding permissions of multiple floating windows based on the determination; launching a system floating window; hiding and containing the multiple floating windows in the system floating window; receiving an activating instruction for the system floating window; extending and displaying the multiple floating windows contained in the system floating window; receiving a selection instruction for the multiple floating windows; displaying a selected floating window of the multiple floating windows; allowing a permission of the selected floating window; and masking a permission of the system floating window.

Abstract: It relates to improved processes of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylate and oxalate thereof. In the present invention, L-glutamic acid or L-glutamic acid sodium salt as the starting material is reacted with chloroactic acid under an alkaline condition via a substitution reaction to obtain compound III; then, compound III is reacted with alcohol in the presence of acid reagent via esterification reaction to obtain compound IV; under the action of strong base, compound IV is subjected to intramolecular condensation into ring, hydrolysis-decarboxylation, and esterification to obtain compound V; compound V is condensed with benzyloxy amine hydrochloride salt in the presence of alkaline to obtain compound VI; compound VI is subjected to reduction and chiral resolution to obtain 5R-[(benzyloxy) amino] piperidine-2S-carboxylate oxalate (IIb) which is then neutralized to obtain 5R-[(benzyloxy) amino] piperidine-2S-carboxylate (IIa).

Abstract: A method for preparing an intermediate for avibactam, and specifically relates to a method for preparing ({[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)tetrabutylammonium salt (II). With 5R-[(benzyloxy) amino] piperidine-2S-carboxylate oxalate (III) as the raw material is reacted with the amide of Formula IV via amidation to prepare the compound of Formula V; the resulting compound of Formula V is reacted with the carbonylation reagent via urea cyclization to obtain the compound of Formula VI; the benzyl or the substituted benzyl in the compound of Formula VI is removed by catalytic hydrogeneration, then the resulting compound is sulfatated by sulfur trioxide complex and is salinized into tetrabutylammonium to obtain the final product (II).

Abstract: A compound of Formula III as the raw material is hydrolyzed in an alkaline condition, then acidized to prepare a compound of Formula IV, and the resulting compound of formula IV and a solid phosgene or diphosgene are concurrently subjected to the urea cyclization and the chloroformylation reaction in the presence of an organic base and a catalyst to obtain a compound of formula V, and then the compound of formula V is amidated to obtain the final product (II). In the present invention, a “one-pot” method is adopted for urea cyclization, chloroformylation, and amidation reaction, and the intermediate products do not need post-treatments such as separation and purification.

Abstract: A method for preparing an intermediate for avibactam, and specifically relates to a method for preparing ({[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)tetrabutylammonium salt (II). With 5R-[(benzyloxy) amino] piperidine-2S-carboxylate oxalate (III) as the raw material is reacted with the amide of Formula IV via amidation to prepare the compound of Formula V; the resulting compound of Formula V is reacted with the carbonylation reagent via urea cyclization to obtain the compound of Formula VI; the benzyl or the substituted benzyl in the compound of Formula VI is removed by catalytic hydrogeneration, then the resulting compound is sulfatated by sulfur trioxide complex and is salinized into tetrabutylammonium to obtain the final product (II).

Abstract: A compound of Formula III as the raw material is hydrolyzed in an alkaline condition, then acidized to prepare a compound of Formula IV, and the resulting compound of formula IV and a solid phosgene or diphosgene are concurrently subjected to the urea cyclization and the chloroformylation reaction in the presence of an organic base and a catalyst to obtain a compound of formula V, and then the compound of formula V is amidated to obtain the final product (II). In the present invention, a “one-pot” method is adopted for urea cyclization, chloroformylation, and amidation reaction, and the intermediate products do not need post-treatments such as separation and purification.

Abstract: It relates to improved processes of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylate and oxalate thereof. In the present invention, L-glutamic acid or L-glutamic acid sodium salt as the starting material is reacted with chloroactic acid under an alkaline condition via a substitution reaction to obtain compound III; then, compound III is reacted with alcohol in the presence of acid reagent via esterification reaction to obtain compound IV; under the action of strong base, compound IV is subjected to intramolecular condensation into ring, hydrolysis-decarboxylation, and esterification to obtain compound V; compound V is condensed with benzyloxy amine hydrochloride salt in the presence of alkaline to obtain compound VI; compound VI is subjected to reduction and chiral resolution to obtain 5R-[(benzyloxy) amino] piperidine-2S-carboxylate oxalate (IIb) which is then neutralized to obtain 5R-[(benzyloxy) amino] piperidine-2S-carboxylate (IIa).

Abstract: The present disclosure relates to the field of electronic devices and provides a charger and an electronic device. The charger includes: a base provided with a holding groove, which is adapted to a back shell of a wearable device and in which a Pogo pin connector is arranged; a first fool-proof structure, which includes a first insert and a second insert. The first insert and the second insert are arranged at the edge of the holding groove. The first insert has a width less than that of the second insert and is used to match with a first locating structure at the side edge of the wearable device. When the charger of the present disclosure charges the wearable device, the fool-proof structure can avoid the misconnection of the positive and negative electrodes in charging and can prevent the Pogo pin connector of the charger from being in direct contact with the Pogo pin connector of the wearable device, which can cause short-circuiting.

Abstract: The disclosure relates to a method and device for displaying a floating window. The method includes monitoring an amount of floating windows that are created on a desktop for respective ones of a plurality of applications; determining that there is more than one of the plurality of applications for which a floating window is created on the desktop; forbidding permissions of multiple floating windows based on the determination; launching a system floating window; hiding and containing the multiple floating windows in the system floating window; receiving an activating instruction for the system floating window; extending and displaying the multiple floating windows contained in the system floating window; receiving a selection instruction for the multiple floating windows; displaying a selected floating window of the multiple floating windows; allowing a permission of the selected floating window; and masking a permission of the system floating window.

Abstract: An information retrieval method, an electronic device and a storage medium are provided. The method comprises: sending at least one keyword in chatting contents in an input box of an instant messenger to a server, when it is detected that the chatting contents need to be sent to a communication counterpart; receiving, from the server based on the at least one keyword, retrieved contents and at least one category in which the retrieved contents are categorically stored in the server; and categorically displaying the retrieved contents in a current interface, in accordance with the at least one category.

Abstract: The present disclosure relates to an application calling management method and apparatus, which pertain to the field of computer technology. The method includes: acquiring a background calling message sent by a first application, the background calling message requesting at least one target application to be called; determining a calling rule corresponding to a current calling, according to the background calling message; if a first calling rule matching the calling rule corresponding to the current calling exists in a terminal-disallowing-calling list, determining from the at least one target application at least one application disallowed to be called according to the first calling rule, where the terminal-disallowing-calling list includes at least one calling rule for controlling disallowance of calling, and the at least one application disallowed to be called is all or some of the at least one target application; and disallowing starting in background the application disallowed to be called.