Patents by Inventor Baowei Chen

Baowei Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240109885
    Abstract: The present invention relates to a 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine derivative, a preparation method therefor, and an application thereof, and in particular to an EGFR inhibitor having the structure of formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use of same as an EGFR inhibitor, and a use of same in the treatment and/or prevention of cancers, tumors, or metastatic diseases at least partially related to EGFR exon 20 insertion or deletion mutations, especially a use in the treatment of hyperproliferative diseases and dysfunction in cell death induction. The definition of each substituent in formula (I) is the same as that in the description.
    Type: Application
    Filed: December 1, 2021
    Publication date: April 4, 2024
    Inventors: Baowei Zhao, Mingming Zhang, Hongping Yu, Zhui Chen, Yaochang Xu
  • Patent number: 9819039
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: November 14, 2017
    Assignee: Battelle Memorial Institute
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Publication number: 20150380757
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Application
    Filed: July 31, 2015
    Publication date: December 31, 2015
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Patent number: 9123931
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: September 1, 2015
    Assignee: Battelle Memorial Institute
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Patent number: 9077011
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: July 7, 2015
    Assignee: Battelle Memorial Institute
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Publication number: 20140234753
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Application
    Filed: April 24, 2014
    Publication date: August 21, 2014
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Publication number: 20140199607
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Application
    Filed: December 13, 2013
    Publication date: July 17, 2014
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Zimin Nie, Baowei Chen, Jianlu Zhang, Guanguang Xia
  • Patent number: 8771856
    Abstract: A redox flow battery having a supporting solution that includes Cl? anions is characterized by an anolyte having V2+ and V3+ in the supporting solution, a catholyte having Fe2+ and Fe3+ in the supporting solution, and a membrane separating the anolyte and the catholyte. The anolyte and catholyte can have V cations and Fe cations, respectively, or the anolyte and catholyte can each contain both V and Fe cations in a mixture. Furthermore, the supporting solution can contain a mixture of SO42? and Cl? anions.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: July 8, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Jianlu Zhang, Baowei Chen, Zimin Nie, Guanguang Xia
  • Patent number: 8628880
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: January 14, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Jianlu Zhang, Baowei Chen, Zimin Nie, Guanguang Xia
  • Publication number: 20120107660
    Abstract: Redox flow battery systems having a supporting solution that contains Cl” ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Application
    Filed: December 28, 2011
    Publication date: May 3, 2012
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Jianlu Zhang, Baowei Chen, Zimin Nie, Guanguang Xia
  • Publication number: 20120077067
    Abstract: A redox flow battery having a supporting solution that includes Cl? anions is characterized by an anolyte having V2+ and V3+ in the supporting solution, a catholyte having Fe2+ and Fe3+ in the supporting solution, and a membrane separating the anolyte and the catholyte. The anolyte and catholyte can have V cations and Fe cations, respectively, or the anolyte and catholyte can each contain both V and Fe cations in a mixture. Furthermore, the supporting solution can contain a mixture of SO42? and Cl? anions.
    Type: Application
    Filed: September 28, 2010
    Publication date: March 29, 2012
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Jianlu Zhang, Baowei Chen, Zimin Nie, Guanguang Xia
  • Publication number: 20120077079
    Abstract: Redox flow battery systems having a supporting solution that contains Cl? ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42? and Cl? ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl? ions or a mixture of SO42? and Cl? ions.
    Type: Application
    Filed: September 28, 2010
    Publication date: March 29, 2012
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Liyu Li, Soowhan Kim, Zhenguo Yang, Wei Wang, Jianlu Zhang, Baowei Chen, Zimin Nie, Guanguang Xia
  • Publication number: 20110300186
    Abstract: Compositions containing an optionally surface-functionalized mesoporous support and a biologically active agent, and pharmaceutical compositions of the same, are provided herein. Such compositions can be useful in the treatment of tumors, for example, by injection of the composition at a location near the site of the tumor.
    Type: Application
    Filed: April 14, 2011
    Publication date: December 8, 2011
    Applicants: Battelle Memorial Institute, University of Washington through its Center for Commercialization
    Inventors: Karl Erik Hellstrom, Ingegerd Hellstrom, Pu Liu, Huafeng Wei, Jun Liu, Chenghong Lei, Baowei Chen, Xiaolin Li