Patents by Inventor Baoxiu Qi

Baoxiu Qi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8354569
    Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: January 15, 2013
    Assignee: University of Bristol
    Inventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
  • Publication number: 20110023185
    Abstract: The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.
    Type: Application
    Filed: July 28, 2010
    Publication date: January 27, 2011
    Applicant: UNIVERSITY OF BRISTOL
    Inventors: ANDREAS RENZ, JÖRG BAUER, MARGIT FRENTZEN, NURSEN SÖZER, STOBART KEITH, THOMAS FRASER, COLIN M. LAZARUS, BAOXIU QI, AMINE ABBADI, ERNST HEINZ
  • Patent number: 7855321
    Abstract: The present invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which code for polypeptides with acyl transferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences which code for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, nucleic acid constructs, vectors and organisms comprising the nucleic acid sequences according to the invention, vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: December 21, 2010
    Assignee: University of Bristol
    Inventors: Andreas Renz, Jörg Bauer, Margit Frentzen, Nursen Sözer, Stobart Keith, Thomas Fraser, Colin M. Lazarus, Baoxiu Qi, Amine Abbadi, Ernst Heinz
  • Patent number: 7714185
    Abstract: The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a transgenic organism, preferably a transgenic plant or a transgenic microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: May 11, 2010
    Assignee: University of Bristol
    Inventors: Jonathan A. Napier, Olga Sayanova, Colin M. Lazarus, Baoxiu Qi, Ernst Heinz, Thorsten Zank, Ulrich Zähringer
  • Patent number: 7601889
    Abstract: This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use. The inventive nucleic acid sequence encodes a polypeptide which elongates ?-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas ?-linolenic acid (C18:3 d6, 9, 12) is not elongated. The invention additionally relates to vectors or organisms comprising an elongase gene having the sequence SEQ ID NO: 1 or its derivatives. The invention further relates to a process for the production of polyunsaturated fatty acids (=PUFAs) with an organism which comprises the elongase gene and which organism produces high amounts of oils and especially oils with a high content of unsaturated fatty acids.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: October 13, 2009
    Inventors: Johnathan A. Napier, Colin M. Lazarus, Baoxiu Qi, Jens Lerchl
  • Publication number: 20060246556
    Abstract: The present invention relates to an improved process for the specific production of poly-unsaturated omega-3 and omega-6 fatty acids and a process for the production of triglycerides having an increased content of unsaturated fatty acids, in particular omega-3 and omega-6 fatty acids having at least two double bonds and a 20 or 22 carbon atom chain length. The invention relates to the production of a transgenic organism, preferably a transgenic plant or a transgenic microorganism, hav-ing an increased content of fatty acids, oils or lipids containing C20- or C22-fatty acids with a delta-5, 7, 8, 10 double bond, respectively due to the expression of a delta-8-desaturase and a delta-9-elon-gase from organisms such as plants preferably Algae like Isochrysis galbana or Euglena gracilis.
    Type: Application
    Filed: December 11, 2003
    Publication date: November 2, 2006
    Applicant: University of Bristol
    Inventors: Johnathan Napier, Olga Sayanova, Colin Lazarus, Baoxiu Qi, Ernst Heinz, Thorsten Zank, Ulrich Zahringer
  • Publication number: 20050089981
    Abstract: This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use. The inventive nucleic acid sequence encodes a polypeptide which elongates ?-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas ?-linolenic acid (C18:3 d6, 9, 12) is not elongated. The invention additionally relates to vectors or organisms comprising an elongase gene having the sequence SEQ ID NO: 1 or its derivatives. The invention further relates to a process for the production of polyunsaturated fatty acids (=PUFAs) with an organism which comprises the elongase gene and which organism produces high amounts of oils and especially oils with a high content of unsaturated fatty acids.
    Type: Application
    Filed: March 26, 2002
    Publication date: April 28, 2005
    Inventors: Johnathan Napier, Colin Lazarus, Baoxiu Qi, Jens Lerchl