Abstract: The invention a fluorinated dendrimer and a preparation method thereof. The preparation method of the fluorinated dendrimer include the following steps: S1, obtaining an intermediate product by addition reaction of 4-fluoroaniline and methyl acrylate at room temperature; S2, stirring the intermediate product with 1,3-diamino-2-propanol and methyl acrylate at room temperature to obtain a mixture; S3, performing a stage heating reaction of the mixture under a reduced pressure condition to obtain the fluorinated dendrimer. The fluorinated dendrimer can solve the problems of high demulsification temperature, large dosage, and low demulsification efficiency of existing demulsifiers.

Abstract: The invention provides cell culture compositions for regulatory T-cells that include particular synthetic peptides. Also provided are methods of treating autoimmune diseases such as age-related macular degeneration and uveitis with regulatory T-cells prepared using said compositions.

Abstract: The invention a fluorinated dendrimer and a preparation method thereof. The preparation method of the fluorinated dendrimer include the following steps: S1, obtaining an intermediate product by addition reaction of 4-fluoroaniline and methyl acrylate at room temperature; S2, stirring the intermediate product with 1,3-diamino-2-propanol and methyl acrylate at room temperature to obtain a mixture; S3, performing a stage heating reaction of the mixture under a reduced pressure condition to obtain the fluorinated dendrimer. The fluorinated dendrimer can solve the problems of high demulsification temperature, large dosage, and low demulsification efficiency of existing demulsifiers.

Abstract: The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and one or more immune tolerance enhancers.

Abstract: The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and transforming growth factor beta, (TGF-?).

Abstract: The invention provides cell culture compositions for regulatory T-cells that include particular synthetic peptides. Also provided are methods of treating autoimmune diseases such as age-related macular degeneration and uveitis with regulatory T-cells prepared using said compositions.

Abstract: The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and one or more immune tolerance enhancers.

Abstract: The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and one or more immune tolerance enhancers.

Abstract: The invention provides methods for treating age-related macular degeneration by administering (i) peptide compositions, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and said peptide compositions. Also provided are methods for diagnosing age-related macular degeneration and monitoring its progression.

Abstract: The invention provides methods for treating age-related macular degeneration by administering (i) peptide compositions, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and said peptide compositions. Also provided are methods for diagnosing age-related macular degeneration and monitoring its progression.

Abstract: The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis.

Abstract: The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis.

Abstract: The present invention is directed to methods of treating and diagnosing age-related macular degeneration.

Abstract: The present invention is directed to methods of diagnosing the presence, severity, or predisposition for development of age-related macular degeneration in a patient based on the frequency of IL-17RC+ cells and or methylation of the promoter of IL17RC gene. Methods of treated age-related macular degeneration are also described.