Patents by Inventor BaoYu Xue

BaoYu Xue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IRAK4 inhibitor and use thereof
    Patent number: 10988482
    Abstract: The present invention relates to a compound inhibiting the activity of an IRAK4 kinase, a pharmaceutical composition thereof, a use thereof in preparing drugs, a method in which same is used for inhibiting the activity of the IRAK4 kinase and a method in which same is used for treating and/or preventing IRAK4 kinase mediated diseases or conditions in mammals (particularly humans). The compound has a structural formula I.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: April 27, 2021
    Assignee: BEIJING HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Baoyu Xue, Runa Zheng, Mi Young Cha, Maengsup Kim
  • IRAK4 INHIBITOR AND USE THEREOF
    Publication number: 20200062775
    Abstract: The present invention relates to a compound inhibiting the activity of an IRAK4 kinase, a pharmaceutical composition thereof, a use thereof in preparing drugs, a method in which same is used for inhibiting the activity of the IRAK4 kinase and a method in which same is used for treating and/or preventing IRAK4 kinase mediated diseases or conditions in mammals (particularly humans). The compound has a structural formula I.
    Type: Application
    Filed: August 13, 2015
    Publication date: February 27, 2020
    Applicant: BEIJING HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Baoyu Xue, Runa Zheng, Mi Young Cha, Maengsup Kim
  • Semi-synthetic conversion of paclitaxel to docetaxel
    Patent number: 7906661
    Abstract: A process is provided for the semi-synthesis of taxane derivatives useful in the preparation of docetaxel, in particular, the semi-synthesis of protected taxane derivatives in a one pot reaction of protecting the C-2?, C-7 and C-10 positions and introducing a t-Boc group at the nitrogen of the amide group at the C-3? position in paclitaxel and subsequently conversion to docetaxel, and derivatives used therein.
    Type: Grant
    Filed: June 29, 2005
    Date of Patent: March 15, 2011
    Assignee: Chatham Biotec, Limited
    Inventors: Ragina Naidu, Samuel Siang Kiang Foo, BaoYu Xue, Bo Fan
  • Semi-synthetic conversion of paclitaxel to docetaxel
    Publication number: 20050288521
    Abstract: A process is provided for the semi-synthesis of taxane derivatives useful in the preparation of docetaxel, in particular, the semi-synthesis of protected taxane derivatives in a one pot reaction of protecting the C-2?, C-7 and C-10 and introducing a t-Boc group at the nitrogen of the amide group at the C-3? position in paclitaxel and subsequently conversion to docetaxel, and derivatives used therein.
    Type: Application
    Filed: June 29, 2004
    Publication date: December 29, 2005
    Applicant: Phytogen Life Sciences Inc.
    Inventors: Ragina Naidu, Samuel Foo, BaoYu Xue, Bo Fan