Patents by Inventor Barak Blum

Barak Blum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MARKERS FOR FUNCTIONALLY MATURE BETA-CELLS AND METHODS OF USING THE SAME
    Publication number: 20140287944
    Abstract: Markers for functionally mature ?-cells and methods of using these markers are disclosed.
    Type: Application
    Filed: February 26, 2014
    Publication date: September 25, 2014
    Applicant: President and Fellows of Harvard College
    Inventors: Sinisa Hrvatin, Douglas A. Melton, Barak Blum
  • METHOD OF TREATING TUMORS
    Publication number: 20120171213
    Abstract: A method of reducing the potential of pluripotent stem cells to generate teratomas in a subject is provided. The method comprises: (a) transplanting a cell population which comprises the pluriptotent stem cells into the subject; and (b) contacting the pluripotent stem cells with an agent that downregulates an activity and/or expression of a polypeptide selected from the group consisting of AW262311 (aka SerpinB6), COX6A1, ZIC2, SOX2, M14087, OTX2, TUBB2B, IL17RD, TMSL8, CRABP1, ZIC3, CDC20, SBK1, TOP2A, DLG7, PTPRZ1, NUF2, NEFL, SPAG5, LOC146909 and survivin (BIRC5), thereby reducing the potential of the pluripotent stem cells to generate teratomas. Methods of treating tumors and compositions capable of same are also provided.
    Type: Application
    Filed: August 31, 2010
    Publication date: July 5, 2012
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim Benvenisty, Barak Blum