Patents by Inventor Barbara A. Brummond

Barbara A. Brummond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassay with novel labeled drug hapten analogues
    Patent number: 5601994
    Abstract: The invention is directed to labeled drug hapten analogues comprising:(A) a label, of the type used in immunoassays, having an amine or sulfhydryl group;(B) a drug hapten nucleus selected from barbiturates or hydantoins and(C) a linking chain linking the 3-position of the drug hapten nucleus to the label through a carbonyl bridge.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: February 11, 1997
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Marsha D. B. Oenick, Ignazio S. Ponticello, Susan J. Danielson, Barbara A. Brummond, David A. Hilborn
  • Immunoassays with novel labeled carbamazepine hapten analogues
    Patent number: 5578457
    Abstract: An immunoassay method and analytical elements for detecting carbamazepine drugs, for example, in body fluids, is described.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: November 26, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Barbara A. Brummond, Mohan S. Saini, Ignazio S. Ponticello
  • Labeled carbamazepine hapten analogues for competitive enzyme immunoassays
    Patent number: 5543311
    Abstract: A labeled carbamazepine analogue is described comprising:(A) a label, of the type used in immunoassays, having an amine or sulfhydryl group such as horseradish peroxidase;(B) a carbamazepine nucleus; and(C) a linking chain linking the carboxamide group of the carbamazepine nucleus to the label, said linking chain having about 4 to about 40 atoms consisting of:(1) C.sub.2 to C.sub.6 alkylene groups; and(2) 5 to 7 membered heterocyclic ring groups, each group being joined into the linking group through chemical groups selected from(a) esters,(b) amides(c) heteroatoms selected from --O--, --S--, and --NR--; wherein R represents hydrogen or C.sub.1 to C.sub.6 alkyl; and(d) carbonyl.The new labeled analogues are useful in immunoassay elements and processes for detection of carbamazepine drugs, for example, in body fluids.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: August 6, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Barbara A. Brummond, Mohan S. Saini, Ignazio S. Ponticello
  • Immunoassays with labeled thyronine hapten analogues
    Patent number: 5527709
    Abstract: The invention is directed to an immunoassay for a thyronine derivative comprising:A. contacting a liquid sample, containing a thyronine derivative, with a labeled thyronine hapten analogue of the derivative in the presence of antibodies for the thyronine derivative under conditions that promote the formation of antibody-thyronine immunocomplexes; andB. determining the bound or unbound quantity of the thyronine derivative in the liquid; characterized in that the labeled thyronine derivative comprises:(i) a label, of the type used in immunoassays, having an amine or sulfhydyl group;(ii) a thyronine nucleus and(iii) a linking chain linking the label to the thyronine nucleus.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: June 18, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Susan J. Danielson, Barbara A. Brummond, Patricia N. Tyminski, Ignazio S. Ponticello
  • Labeled drug hapten analogues for immunoassays
    Patent number: 5298403
    Abstract: The invention is directed to labeled drug hapten analogues comprising:(A) a label, of the type used in immunoassays, having an amine or sulfhydryl group;(B) a drug hapten nucleus selected from barbiturates or hydantoins and(C) a linking chain linking the 3-position of the drug hapten nucleus to the label through a carbonyl bridge.
    Type: Grant
    Filed: March 16, 1992
    Date of Patent: March 29, 1994
    Assignee: Eastman Kodak Company
    Inventors: Susan J. Danielson, Barbara A. Brummond, Marsha D. B. Oenick, Ignazio S. Ponticello, David A. Hilborn