Patents by Inventor Barbara A. Israel

Barbara A. Israel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Devices for cell assays
    Patent number: 9968935
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: May 15, 2018
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Josh Sotos, Doug Hansmann, Renee Herber, Joseph Burkholder, Keren Hulkower, Michael Bonds
  • SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS
    Publication number: 20180052111
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assays format.
    Type: Application
    Filed: October 23, 2017
    Publication date: February 22, 2018
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Liquid crystal based analyte detection
    Patent number: 9816147
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: November 14, 2017
    Assignee: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Anhalt, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
  • Substrates, devices, and methods for quantitative liquid crystal assays
    Patent number: 9797843
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: October 24, 2017
    Assignee: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS
    Publication number: 20160025636
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: July 28, 2015
    Publication date: January 28, 2016
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Substrates, devices, and methods for quantitative liquid crystal assays
    Patent number: 9103794
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: August 11, 2015
    Assignee: PLATYPUS TECHNOLOGIES LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • LIQUID CRYSTAL BASED ANALYTE DETECTION
    Publication number: 20150203925
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Application
    Filed: March 19, 2015
    Publication date: July 23, 2015
    Inventors: Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
  • Liquid crystal based analyte detection
    Patent number: 8988620
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: March 24, 2015
    Assignee: Platypus Technologies, LLC
    Inventors: Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
  • METHOD FOR ASSAYING CELL MOVEMENT
    Publication number: 20130344582
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: August 19, 2013
    Publication date: December 26, 2013
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Method for assaying cell movement
    Patent number: 8512974
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for analyzing cell invasion.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 20, 2013
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • METHOD FOR ASSAYING CELL MOVEMENT
    Publication number: 20130040332
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 14, 2013
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Method for assaying cell movement
    Patent number: 8268614
    Abstract: The present invention relates to the field of assays of cell movement. In particular, the present invention provides methods for assaying cell movement where inserts are used to confine cells to a defined area in a well of a multiwell plate and movement from the defined area is assayed.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: September 18, 2012
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbot
  • SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS
    Publication number: 20120135450
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: February 8, 2012
    Publication date: May 31, 2012
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Substrates, devices, and methods for cellular assays
    Patent number: 7842499
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: November 30, 2010
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS
    Publication number: 20100221815
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: January 27, 2010
    Publication date: September 2, 2010
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Substrates, devices, and methods for quantitative liquid crystal assays
    Patent number: 7666661
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assasy format.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: February 23, 2010
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Compositions and liquid crystals
    Patent number: 7662572
    Abstract: The present invention relates to compounds, compositions, and methods in the field of detection of analytes. In particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: February 16, 2010
    Assignee: Platypus Technologies, LLC.
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • LIQUID CRYSTAL BASED ANALYTE DETECTION
    Publication number: 20100009344
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Application
    Filed: August 31, 2009
    Publication date: January 14, 2010
    Applicant: PLATYPUS TECHNOLOGIES, LLC
    Inventors: Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
  • Bead based assays using a liquid crystal reporter
    Patent number: 7531366
    Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: May 12, 2009
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann
  • DEVICES FOR CELL ASSAYS
    Publication number: 20090054262
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 26, 2009
    Applicant: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Josh Sotos, Doug Hansmann, Renee Herber, Joseph Burkholder, Karen Hulkower, Michael Bonds