Patents by Inventor Barbara A. Krulewicz

Barbara A. Krulewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enantioselective bioreduction using yeast
    Patent number: 6121026
    Abstract: The invention relates to a class of enantiomerically pure intermediates represented by Formula I, where X is F, Cl, Br, or I, and a novel enantioselective bioreductive process using yeast to form these intermediates, which are useful in the synthesis of endothelin antagonists, and the like.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: September 19, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Michel M. Chartrain, Barbara A. Krulewicz, Paul N. Devine, David M. Tschaen