Patents by Inventor Barbara A. Pio

Barbara A. Pio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazoles
    Patent number: 6953793
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: October 11, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 6951851
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: October 4, 2005
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 6949540
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: September 27, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 6936603
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: August 30, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P Meduna, Barbara A. Pio, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20050101587
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: September 5, 2001
    Publication date: May 12, 2005
    Inventors: Christopher Butler, Hui Cai, James Edwards, Cheryl Grice, Yin Gu, Darin Gustin, Lars Karlsson, Haripada Khatuya, Steven Meduna, Barbara Pio, Clark Sehon, Siquan Sun, Kevin Tays, Robin Thurmond, Jianmei Wei
  • Heterocyclic compounds
    Publication number: 20050085487
    Abstract: Heterocyclic compounds and methods of making them and using them.
    Type: Application
    Filed: October 8, 2004
    Publication date: April 21, 2005
    Inventors: Nicholas Carruthers, Wenying Chai, Curt Dvorak, James Edwards, Cheryl Grice, Jill Jablonowski, Lars Karlsson, Haripada Khatuya, Jennifer Kreisberg, Annette Kwok, Timothy Lovenberg, Kiev Ly, Barbara Pio, Chandravadan Shah, Siquan Sun, Robin Thurmond, Jianmei Wei, Wei Xiao
  • Heterocyclic compounds
    Patent number: 6803362
    Abstract: Heterocyclic compounds and methods of making them and using them.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: October 12, 2004
    Assignee: Ortho-McNeil Pharmaceutical inc.
    Inventors: Nicholas I. Carruthers, Wenying Chai, Curt A. Dvorak, James P. Edwards, Cheryl A. Grice, Jill A. Jablonowski, Lars Karlsson, Haripada Khatuya, Jennifer D. Kreisberg, Annette K. Kwok, Timothy W. Lovenberg, Kiev S. Ly, Barbara Pio, Chandravadan R. Shah, Siguan Sun, Robin L. Thurmond, Jianmei Wei, Wei Xiao
  • Heterocyclic compounds
    Publication number: 20040058934
    Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 25, 2004
    Inventors: Nicholas I. Carruthers, Curt A. Dvorak, James P. Edwards, Cheryl A. Grice, Jill A. Jablonowski, Kiev S. Ly, Barbara A. Pio, Chandravadan R. Shah, Jennifer D. Venable
  • Substituted pyrazoles
    Publication number: 20040044027
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Application
    Filed: August 8, 2003
    Publication date: March 4, 2004
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20030229075
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Application
    Filed: March 28, 2003
    Publication date: December 11, 2003
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20030225063
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Application
    Filed: March 28, 2003
    Publication date: December 4, 2003
    Applicant: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20030225062
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Application
    Filed: March 28, 2003
    Publication date: December 4, 2003
    Applicant: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Heterocyclic compounds
    Publication number: 20030207893
    Abstract: Heterocyclic compounds and methods of making them and using them.
    Type: Application
    Filed: March 8, 2002
    Publication date: November 6, 2003
    Inventors: Nicholas I. Carruthers, Wenying Chai, Curt A. Dvorak, James P. Edwards, Cheryl A. Grice, Jill A. Jablonowski, Lars Karlsson, Haripada Khatuya, Jennifer D. Kreisberg, Annette K. Kwok, Timothy W. Lovenberg, Kiev S. Ly, Barbara Pio, Chandravadan R. Shah, Siquan Sun, Robin L. Thurmond, Jianmei Wei, Wei Xiao
  • Substituted pyrazoles
    Patent number: 6635633
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: October 21, 2003
    Assignee: Ortho-Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P. Meduna, Barbara A. Pio, Jianmei Wei
  • Androgen receptor modulator compounds and methods
    Publication number: 20030186970
    Abstract: Compounds, pharmaceutical compositions, and methods for modulating processes mediated by steroid receptors. In particular, preparation and methods of use of non-steroidal compounds and compositions that are agonists, partial agonists, and antagonists for the androgen receptor (AR) are described. Further, described are the methods of making and use of critical intermediates including a stereoselective synthetic route to intermediates for the AR modulators.
    Type: Application
    Filed: September 9, 2002
    Publication date: October 2, 2003
    Inventors: Robert Higuchi, Kristen L. Arienti, Mani Neelakandha, Barbara Pio, Lin Zhi, Penghui Chen, Thomas R. Caferro
  • Bicyclic androgen and progesterone receptor modulator compounds and methods
    Publication number: 20030130505
    Abstract: The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 10, 2003
    Inventors: Lin Zhi, Christopher Tegley, Barbara Pio, Cornelis Arjan Van Oerveren, Mehrnouch Motamedi, Esther Martinborough, Sarah West, Robert Higuchi, Lawrence G. Hamann, Luc Farmer
  • Method for treating allergies using substituted pyrazoles
    Patent number: 6583155
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: June 24, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Patent number: 6579896
    Abstract: A method for the treatment of an allergic condition, including an an atopic allergic conditions, using substituted pyrazoles.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: June 17, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Yin Gu, Lars Karlsson, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Robin L. Thurmond, Jianmei Wei
  • Bicyclic androgen and progesterone receptor modulator compounds and methods
    Patent number: 6566372
    Abstract: The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: May 20, 2003
    Assignee: Ligand Pharmaceuticals Incorporated
    Inventors: Lin Zhi, Christopher Tegley, Barbara Pio, Cornelis Arjan Van Oeveren, Mehrnouch Motamedi, Esther Martinborough, Sarah West
  • Substituted pyrazoles
    Publication number: 20030078419
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Application
    Filed: August 10, 2001
    Publication date: April 24, 2003
    Inventors: Christopher R. Butler, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Clark A. Sehon, Kevin L. Tays, Jianmei Wei