Patents by Inventor Barbara A. Qurollo

Barbara A. Qurollo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7202085
    Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: April 10, 2007
    Assignee: Calgene LLC
    Inventors: Tim N. Oulmassov, Kevin E. McBride, Paula C. Miller, John C. Anderson, Lyle D. Crossland, Thomas H. Adams, Barbara A. Qurollo, Victoria Gavrias
  • Publication number: 20050227285
    Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
    Type: Application
    Filed: June 3, 2005
    Publication date: October 13, 2005
    Inventors: Tim Oulmassov, Kevin McBride, Paula Miller, John Anderson, Lyle Crossland, Thomas Adams, Barbara Qurollo, Victoria Gavrias
  • Patent number: 6943243
    Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: September 13, 2005
    Assignee: Calgene LLC
    Inventors: Tim N. Oulmassov, Kevin E. McBride, Paula C. Miller, John C. Anderson, Lyle D. Crossland, Thomas H. Adams, Barbara A. Qurollo, Victoria Gavrias
  • Publication number: 20030224483
    Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
    Type: Application
    Filed: February 6, 2003
    Publication date: December 4, 2003
    Inventors: Tim N. Oulmassov, Kevin E. McBride, Paula C. Miller, John C. Anderson, Lyle D. Crossland, Thomas H. Adams, Barbara A. Qurollo, Victoria Gavrias
  • Publication number: 20030096246
    Abstract: Isolated telomeres from the linear chromosome of an Agrobacterium tumefaciens are obtainable from a restriction enzyme fragment at the end of said chromosome which is less than 4,000 nucleotide bases and comprises a segment of consecutive nucleotide bases having substantial identity to SEQ ID NO: 1 or SEQ ID NO: 2. The isolated telomeres are obtained by removing more or less of the segment from the larger restriction fragment. Pairs of isolated and distinct telomeres obtained from opposite ends of the linear chromosome are used for linear DNA constructs for use in producing transgenic plants by Agrobacterium tumefaciens transformation. Such constructs act as linear plasmids and comprise at least an origin of replication and terminal regions obtained from telomeres.
    Type: Application
    Filed: November 26, 2001
    Publication date: May 22, 2003
    Inventors: Steven C. Slater, Barbara A. Qurollo
  • Patent number: 6518066
    Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (“lux box”) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: February 11, 2003
    Assignee: Calgene LLC
    Inventors: Tim N. Oulmassov, Kevin E. McBride, Paula C. Miller, John C. Anderson, Lyle D. Crossland, Thomas H. Adams, Barbara A. Qurollo, Victoria Gavrias