Patents by Inventor Barbara Alter

Barbara Alter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of culturing lymphocytes and method of treatment using such lymphocytes
    Patent number: 5443983
    Abstract: In accordance with the present invention, a method of culturing lymphocytes is disclosed in which the lymphocytes are cultured in the presence of interleukin-2 (IL-2) and an antibody to a lymphocyte surface receptor, preferably an antibody to a lymphocyte T3 surface receptor. Preferably, the antibody is monoclonal. Cells cultured with anti-CD3 maintain their LAK activity as they increase in number. The cells can also be cultured in the presence of an additional lymphokine to obtain additional LAK activity.Methods of medical treatment are also disclosed in which cells cultured in accordance with the culturing methods of the present invention are introduced into the individual to be treated.
    Type: Grant
    Filed: March 21, 1988
    Date of Patent: August 22, 1995
    Assignee: Regents of the University of Minnesota
    Inventors: Augusto C. Ochoa, Fritz H. Bach, Barbara Alter, Paul Sondel