Patents by Inventor Barbara Anne Swanson

Barbara Anne Swanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-hepcidin antibodies and uses thereof
    Patent number: 8765129
    Abstract: Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: July 1, 2014
    Assignee: Eli Lilly and Company
    Inventors: Donmienne Doen Mun Leung, Peng Luan, Barbara Anne Swanson, Ying Tang, Derrick Ryan Witcher
  • Anti-hepcidin antibodies and uses thereof
    Patent number: 8329174
    Abstract: Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: December 11, 2012
    Assignee: Eli Lilly and Company
    Inventors: Donmienne Doen Mun Leung, Barbara Anne Swanson, Ying Tang, Peng Luan, Derrick Ryan Witcher
  • Anti-sclerostin antibodies
    Patent number: 8257704
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: September 4, 2012
    Assignee: Eli Lilly and Company
    Inventors: Andrew Ihor Korytko, David Matthew Marquis, Eric Michael Smith, Barbara Anne Swanson
  • DKK-1 antibodies
    Patent number: 8148498
    Abstract: The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: April 3, 2012
    Assignee: Eli Lilly and Company
    Inventors: Marcio Chedid, Ryan James Darling, Rachelle Jeanette Galvin, Barbara Anne Swanson
  • ANTI-SCLEROSTIN ANTIBODIES
    Publication number: 20110250205
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 13, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: Andrew Ihor KORYTKO, David Matthew MARQUIS, Eric Michael SMITH, Barbara Anne SWANSON
  • Methods of treatment comprising administering an anti-sclerostin antibody
    Patent number: 7988970
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: August 2, 2011
    Assignee: Eli Lilly and Company
    Inventors: Andrew Ihor Korytko, David Matthew Marquis, Eric Michael Smith, Barbara Anne Swanson
  • ANTI-HEPCIDIN ANTIBODIES AND USES THEREOF
    Publication number: 20110027261
    Abstract: Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
    Type: Application
    Filed: August 31, 2010
    Publication date: February 3, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: Donmienne Doen Mun Leung, Barbara Anne Swanson, Ying Tang, Peng Luan, Derrick Ryan Witcher
  • Anti-hepcidin antibodies and uses thereof
    Patent number: 7820163
    Abstract: Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
    Type: Grant
    Filed: October 29, 2008
    Date of Patent: October 26, 2010
    Assignee: Eli Lilly and Company
    Inventors: Donmienne Doen Mun Leung, Barbara Anne Swanson, Ying Tang, Peng Luan, Derrick Ryan Witcher
  • DKK-1 ANTIBODIES
    Publication number: 20100260754
    Abstract: The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
    Type: Application
    Filed: April 6, 2010
    Publication date: October 14, 2010
    Applicant: ELI LILLY AND COMPANY
    Inventors: Marcio CHEDID, Ryan James DARLING, Rachelle Jeanette GALVIN, Barbara Anne Swanson
  • Anti-Sclerostin Antibodies
    Publication number: 20100221263
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Application
    Filed: May 13, 2010
    Publication date: September 2, 2010
    Applicant: ELI LILLY AND COMPANY
    Inventors: Andrew Ihor Korytko, David Matthew Marquis, Eric Michael Smith, Barbara Anne Swanson
  • Anti-sclerostin antibodies
    Patent number: 7744874
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: June 29, 2010
    Assignee: Eli Lilly and Company
    Inventors: Andrew Ihor Korytko, David Matthew Marquis, Eric Michael Smith, Barbara Anne Swanson
  • ANTI-HEPCIDIN ANTIBODIES AND USES THEREOF
    Publication number: 20090136495
    Abstract: Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
    Type: Application
    Filed: October 29, 2008
    Publication date: May 28, 2009
    Inventors: Dennis Patrick Gately, Donmienne Doen Mun Leung, Barbara Anne Swanson, Ying Tang, YuPing Anthony Cai, LuHong He, Peng Luan, Derrick Ryan Witcher
  • ANTI-SCLEROSTIN ANTIBODIES
    Publication number: 20090060924
    Abstract: Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
    Type: Application
    Filed: March 11, 2008
    Publication date: March 5, 2009
    Inventors: Andrew Ihor Korytko, David Matthew Marquis, Eric Michael Smith, Barbara Anne Swanson