Patents by Inventor Barbara Boyan

Barbara Boyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODIFYING IN VIVO CALCIFICATION OF HYDROGELS
    Publication number: 20160074557
    Abstract: Provided herein according to some embodiments of the invention are methods of inhibiting or preventing calcification of hydrogels. Such methods may include combining the hydrogel with a buffer solution having a pH lower than 7.4; forming hydrogel by crosslinking alginate in a solution comprising a bisphosphonate compound; and/or forming hydrogel by crosslinking polyanionic polymer with a polyvalent cation that is not Ca2+. Compositions that may be used in such methods are also provided herein. Also provided herein according to some embodiments of the invention are methods of bone regeneration and/or formation that include administering hydrogel that does not encapsulate biological material that affects calcification and/or bone formation to an area of a subject's body that is in need of bone formation and/or regeneration.
    Type: Application
    Filed: April 28, 2015
    Publication date: March 17, 2016
    Inventors: Zvi Schwartz, Christopher S.D. Lee, Hunter R. Moyer, Barbara Boyan
  • Biomolecular coating for implants
    Patent number: 8445006
    Abstract: Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an ?2?1 or ?5?1 integrin-specific ligand are provided. The substrates and devices coated with an ?2?1 or ?5?1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: May 21, 2013
    Assignee: Georgia Tech Research Corporation
    Inventors: Andrés J. Garcia, Catherine D. Reyes, Timothy Petrie, Zvi Schwartz, Barbara Boyan, Jenny E. Raynor, David M. Collard, Abigail M. Wojtowicz, Robert E. Guldberg
  • Microencapsulation of Cells in Hydrogels Using Electrostatic Potentials
    Publication number: 20080031962
    Abstract: Compositions and methods for producing encapsulated cells having an average diameter of less than about 200 ?m are provided.
    Type: Application
    Filed: October 7, 2005
    Publication date: February 7, 2008
    Inventors: Barbara Boyan, Ramsey Kinney, Zvi Schwartz
  • Load bearing biocompatible device
    Publication number: 20050273178
    Abstract: Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
    Type: Application
    Filed: February 7, 2005
    Publication date: December 8, 2005
    Inventors: Barbara Boyan, Robert Guldberg, Stephen Kennedy, David Ku
  • Surface directed cellular attachment
    Publication number: 20050196452
    Abstract: Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
    Type: Application
    Filed: February 7, 2005
    Publication date: September 8, 2005
    Inventors: Barbara Boyan, Stephen Kennedy