Patents by Inventor Barbara Dunn

Barbara Dunn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
    Patent number: 5643763
    Abstract: The present invention provides methods for construction of recombinant Yeast Artificial Chromosomes ("YAC") by homologous recombination between YACs during meiosis. In particular, conditions are provided for the step of mating haploid cells and for the step of spore analysis that increase the frequency of spores containing the desired recombinant YAC. The methods find particular use in constructing recombinant YACs between YACs that are incompatible when co-propagated in a diploid and/or that share homology regions of less than about 50 kilobases. Linking YACs, methods of their construction, and methods of their use are provided that allow facile construction of a YAC containing two or more discontinuous regions of DNA.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: July 1, 1997
    Assignee: Genpharm International, Inc.
    Inventors: Barbara Dunn, Theodore K. Choi