Patents by Inventor Barbara E. Slack

Barbara E. Slack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying agents which regulate release of amyloid precursor protein
    Patent number: 6329155
    Abstract: Amyloid precursor protein (APP) processing which is activated by cell-surface neurotransmitter receptors, is described. An assay for testing an agent for the capacity to regulate, and particularly to stimulate, secretion of amyloid precursor protein (APP), a description of the characteristics of agents identified by the assay, and a method of altering APP processing in an individual are also disclosed. The assay, agents, and method of altering APP processing are particularly useful for the treatment and prevention of diseases involving APP processing, such as Alzheimer's disease.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: December 11, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Roger M. Nitsch, Barbara E. Slack, Richard J. Wurtman, John H. Growdon