Patents by Inventor Barbara Ecabert

Barbara Ecabert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DOSE REGIMEN OF VICASINABIN
    Publication number: 20250195528
    Abstract: The present invention relates to (3S)-1-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-ol for use in the treatment of diabetic retinopathy, and its methods of treatment thereof.
    Type: Application
    Filed: February 27, 2025
    Publication date: June 19, 2025
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Katrijn Bogman, Antonello Luigi Girolamo Caruso, Barbara Ecabert, Andreas Guenther, Ulrich Friedrich Oskar Luhmann, Agnès Poirier, Bernhard Steiert, Christoph Ullmer
  • METHOD FOR MONITORING CATHEPSIN S INHIBITION
    Publication number: 20170192000
    Abstract: The present invention relates to a method for monitoring Cathepsin S inhibitor activity in tissue samples of animals comprising: a) providing a tissue sample of an animal to whom a Cathepsin S inhibitor has been administered or providing a tissue sample of an animal that was contacted in vitro with a Cathepsin S inhibitor, wherein the tissue samples comprise white blood cells, b) measuring li p10 peptide level in white blood cells of the tissue sample of step a) by flow cytometry and c) correlating li p10 peptide level in white blood cells to Cathepsin S inhibitor dose, wherein a Cathepsin S inhibitor leads to increased level of li p10 peptide in the white blood cells.
    Type: Application
    Filed: March 10, 2017
    Publication date: July 6, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ana Patricia BENTO PEREIRA DA SILVA, Sebastian DZIADEK, Barbara ECABERT, Michael GERG, Everson NOGOCEKE, Moritz MARCINOWSKI, Bernhard REIS, Thomas SCHINDLER, Michel Achille Edouard THERON
  • ANTIBODY BINDING TO ABCA1 POLYPEPTIDE
    Publication number: 20120322083
    Abstract: The invention relates to an isolated antibody that binds to native ABCA1 polypeptide and its uses for the detection of ABCA1 polypeptides in tissue samples.
    Type: Application
    Filed: June 14, 2012
    Publication date: December 20, 2012
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Barbara Ecabert, Hugues Matile, Everson Nogoceke, Bernhard Reis, Haiyan Wang