Patents by Inventor Barbara Felber

Barbara Felber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Altering the immundominance hierarchy using a DNA vaccine expressing conserved regions
    Patent number: 11167025
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: November 9, 2021
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • Altering the Immundominance Hierarchy Using a DNA Vaccine Expressing Conserved Regions
    Publication number: 20190381166
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 19, 2019
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • Altering the immundominance hierarchy using a DNA vaccine expressing conserved regions
    Patent number: 10426830
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: October 1, 2019
    Assignees: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, UNIVERSITY OF WASHNGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • Altering the Immundominance Hierarchy Using a DNA Vaccine Expressing Conserved Regions
    Publication number: 20170028056
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Application
    Filed: August 12, 2016
    Publication date: February 2, 2017
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • Method of altering the immundominance hierarchy of HIV gag by DNA vaccine expressing conserved regions
    Patent number: 9415099
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: August 16, 2016
    Assignees: The United States of America as Represented by the Secretary of the Department of Health and Human Services, University of Washington through its Center for Commercialization
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • METHOD OF ALTERING THE IMMUNDOMINANCE HIERARCHY OF HIV GAG BY DNA VACCINE EXPRESSING CONSERVED REGIONS
    Publication number: 20150056237
    Abstract: The invention provides methods and compositions for eliciting broad immune responses. The methods employ nucleic acid vaccines that encodes highly conserved elements from a virus.
    Type: Application
    Filed: March 4, 2013
    Publication date: February 26, 2015
    Inventors: George Pavlakis, Barbara Felber, James Mullins
  • DNA immunization protocols
    Patent number: 8586055
    Abstract: This invention provides DNA vaccines for the treatment of patients undergoing anti-retroviral therapy. The vaccines are surprisingly effective at controlling viremia.
    Type: Grant
    Filed: January 14, 2008
    Date of Patent: November 19, 2013
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Barbara Felber, George N. Pavlakis
  • Potent combinations of mRNA transport elements
    Patent number: 8163542
    Abstract: This invention provides expression vectors that comprise a combination of RNA transport elements that improve expression.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: April 24, 2012
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Barbara Felber, Sergey V. Smulevitch, George Pavlakis
  • IL-12 for expression in mammalian cell
    Patent number: 7833754
    Abstract: The present invention provides for nucleic acids improved for the expression of interleukin-12 (IL-12) in mammalian cells. The invention further provides for methods of expressing IL-12 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-12 sequence.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: November 16, 2010
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Barbara Felber, George N. Pavlakis, Margherita Rosati
  • DNA VACCINATION PROTOCOLS
    Publication number: 20100285061
    Abstract: This invention provides DNA vaccines for the treatment of patients undergoing anti-retroviral therapy. The vaccines are surprisingly effective at controlling viremia.
    Type: Application
    Filed: January 14, 2008
    Publication date: November 11, 2010
    Applicant: The Government of the United States, as represented by The Secretary of The Department ...
    Inventors: Barbara Felber, George N. Pavlakis
  • IL-12 for Expression in Mammalian Cell
    Publication number: 20090137005
    Abstract: The present invention provides for nucleic acids improved for the expression of interleukin-12 (IL-12) in mammalian cells. The invention further provides for methods of expressing IL-12 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-12 sequence.
    Type: Application
    Filed: January 12, 2007
    Publication date: May 28, 2009
    Applicant: The Government of the United States of America, as a representative by the Secretary of the Depart
    Inventors: Barbara Felber, George N. Pavlakis, Margherita Rosati
  • Potent combinations of mrna transport elements
    Publication number: 20070031921
    Abstract: This invention provides expression vectors that comprise a combination of RNA transport elements that improve expression.
    Type: Application
    Filed: May 19, 2004
    Publication date: February 8, 2007
    Applicant: The Government of the United States, as represent by The Secretary of Health and Human Services
    Inventors: Barbara Felber, Sergey Smulevitch, George Pavlakis