Patents by Inventor Barbara Garvik

Barbara Garvik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vectors for expressing in vivo biotinylated recombinant proteins
    Patent number: 7795411
    Abstract: The present invention provides compositions and methods for generating in vivo biotinylated, secreted recombinant polypeptides comprising recombinantly co-expressing in a yeast cell (a) a secreted recombinant polypeptide comprising a biotin accepting site; and (b) a biotin ligase fused to the golgi localization domain so that the biotin ligase is localized to the golgi of the yeast cell where it acts on the biotin-accepting site of the secreted polypeptide as it transits the secretory system.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: September 14, 2010
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Nathalie Scholler, Barbara Garvik