Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: In some embodiments, the power generator for converting mechanical energy to electrical energy may include a compressible element adapted and configured to be placed in an environment having a variable compressive force such as varying ambient pressures. The compressible element may be compressed by a force applied by the variable pressure to the compressible element. The power generator may further include a transducer that may be coupled to the compressible element and that may convert mechanical energy from the compression of the compressible element to electrical energy. In some embodiments, the power generator may be adapted to be an implantable power generator for converting mechanical energy from a patient to electrical energy, such that the compressible element adapted and configured to be placed between two adjacent tissue layers of the patient and to be compressed by a force applied from the two adjacent tissue layers to the compressible element.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: In some embodiments, the power generator for converting mechanical energy to electrical energy is described may include a compressible element adapted and configured to be placed in an environment having a variable compressive force such as varying ambient pressures. The compressible element may be compressed by a force applied by the variable pressure to the compressible element. The power generator may further include a transducer that may be coupled to the compressible element and that may convert mechanical energy from the compression of the compressible element to electrical energy. In some embodiments, the power generator may be adapted to be an implantable power generator for converting mechanical energy from a patient to electrical energy, such that the compressible element adapted and configured to be placed between two adjacent tissue layers of the patient and to be compressed by a force applied from the two adjacent tissue layers to the compressible element.

Abstract: The present invention provides a demineralized bone carrier matrix which is tolerant of bending, stretching and compression. The material comprises a carrier base material cross-linked with a multifunctional polymer. Demineralized bone matrix may be dispersed with the carrier matrix. The demineralized bone carrier matrix may be used as a bone graph substitute. Methods for making the carrier matrix are also provided.

Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.

Abstract: A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.

Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

Abstract: The present invention provides a demineralized bone carrier matrix which is tolerant of bending, stretching and compression. The material comprises a carrier base material cross-linked with a multifunctional polymer. Demineralized bone matrix may be dispersed with the carrier matrix. The demineralized bone carrier matrix may be used as a bone graph substitute. Methods for making the carrier matrix are also provided.

Abstract: In some embodiments, the power generator for converting mechanical energy to electrical energy is described may include a compressible element adapted and configured to be placed in an environment having a variable compressive force such as varying ambient pressures. The compressible element may be compressed by a force applied by the variable pressure to the compressible element. The power generator may further include a transducer that may be coupled to the compressible element and that may convert mechanical energy from the compression of the compressible element to electrical energy. In some embodiments, the power generator may be adapted to be an implantable power generator for converting mechanical energy from a patient to electrical energy, such that the compressible element adapted and configured to be placed between two adjacent tissue layers of the patient and to be compressed by a force applied from the two adjacent tissue layers to the compressible element.

Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

Abstract: An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or random times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates.

Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

Abstract: A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.