Patents by Inventor Barbara Helen Hosein

Barbara Helen Hosein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides effective for diagnosis and detection of hepatitis C infection
    Patent number: 5736321
    Abstract: The present invention relates to novel linear and branched peptides specific for the diagnosis and prevention of hepatitis C virus (HCV) infection. More particularly, the present invention is directed to linear and branched synthetic peptides containing at least one antigenic site which is effective for detecting HCV-associated antibodies in patients using immunoassay techniques. In some cases, these peptides are also library peptides with degenerate amino acid positions. Preferred mixtures for detection of HCV antibodies are provided as well as a novel spliced peptide useful for blocking the non-specific reactivity of certain NS-3 conformational epitopes.
    Type: Grant
    Filed: September 19, 1995
    Date of Patent: April 7, 1998
    Assignee: United Biomedical, Inc.
    Inventors: Barbara Helen Hosein, Chang Yi Wang
  • Linear and branched peptides effective in diagnosing and detecting non-A, non-B hepatitis
    Patent number: 5639594
    Abstract: The present invention relates to novel linear and branched peptides specific for the diagnosis and prevention of non-A, non-B hepatitis (NANBH), as well as hepatitis C virus (HCV) infection. More particularly, the present invention is directed to linear peptides diagnostic for NS-3 of HCV as well as branched synthetic substituted and hybrid peptides containing at least one epitope which is effective in detecting NANBH-associated antibodies in patients with NANBH using immunoassay techniques. In addition, this invention provides immunoassays for the detection and diagnosis of NANBH using the subject peptides, vaccine compositions for prevention and treatment of NANBH or HCV infection as well as a method of treating or preventing NANBH and HCV infection.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: June 17, 1997
    Assignee: United Biomedical, Inc.
    Inventors: Chang Yi Wang, Barbara Helen Hosein