Patents by Inventor Barbara Horsey O'Connor

Barbara Horsey O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20210292419
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 23, 2021
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 10954303
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: March 23, 2021
    Assignee: BIOGEN MA INC.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20180194843
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: March 7, 2018
    Publication date: July 12, 2018
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20150044206
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: October 27, 2014
    Publication date: February 12, 2015
    Applicant: BIOGEN IDEC MA INC.
    Inventors: David J. BURKE, Shaun E. BUCKLEY, Sherwood Russ LEHRMAN, Barbara Horsey O'CONNOR, James CALLAWAY, Christopher P. PHILLIPS
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 8900577
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: December 2, 2014
    Assignee: Biogen Idec Ma Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Method for treating multiple sclerosis and crohn's disease
    Patent number: 8815236
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: August 26, 2014
    Assignee: Biogen Idec MA Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 8349321
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: January 8, 2013
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunoglobulin Formulation and Method of Preparation Thereof
    Publication number: 20120328614
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: September 6, 2012
    Publication date: December 27, 2012
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20100021461
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: October 2, 2009
    Publication date: January 28, 2010
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: David J. BURKE, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway
  • Lyophilized Immunoglobulin Formulations and Methods of Preparation
    Publication number: 20090208492
    Abstract: The present invention relates generally to the field of pharmaceutical formulation of immunoglobulins. Specifically, the present invention relates to stable, lyophilized, high concentration immunoglobulin formulations. This invention is exemplified by a stabilized lyophilized formulation of the recombinant humanized anti-alpha-4 integrin antibody natalizumab.
    Type: Application
    Filed: June 12, 2008
    Publication date: August 20, 2009
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: Barbara Horsey O'Connor, Shaun E. Buckley, David Burke
  • Hydrogel particle formulation
    Patent number: 7022313
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: April 4, 2006
    Assignee: PowderJect Research Ltd.
    Inventors: Barbara Horsey O'Connor, Terry Lee Burkoth, Steven Joseph Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner
  • Hydrogel particle formulation
    Publication number: 20020061336
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Application
    Filed: August 3, 2001
    Publication date: May 23, 2002
    Inventors: Barbara Horsey O'Connor, Terry Lee Burkoth, Steven Joseph Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner