Patents by Inventor Barbara Imperiali

Barbara Imperiali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescence assay for kinase activity
    Patent number: 7262282
    Abstract: The present invention provides a sensor and methods for determining kinase activity.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: August 28, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Barbara Imperiali, Melissa D. Shults
  • Fluorescent probes for biological studies
    Publication number: 20060234206
    Abstract: The present invention provides fluorescent compounds of formula (I) and methods monitoring protein-protein interactions.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 19, 2006
    Inventors: Barbara Imperiali, Eugenio Vazquez
  • Lanthanide binding tags
    Patent number: 7101667
    Abstract: The present invention provides lanthanide binding tags (LBT) that selectively complex trivalent lanthanide (Ln) ions and afford stable complexes with desirable physical properties, including at least one of fluorescence and anomalous x-ray scattering.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: September 5, 2006
    Assignees: Massachusetts Institute of Technology, Trustees of Boston University
    Inventors: Barbara Imperiali, Karen N. Allen, Katherine J. Franz
  • Fluorescence assay for kinase activity
    Patent number: 6906194
    Abstract: The present invention provides a sensor and methods for determining kinase activity.
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: June 14, 2005
    Assignee: Massachusetts Instititue of Technology
    Inventors: Barbara Imperiali, Melissa D. Shults
  • Fluorescence assay for kinase activity
    Publication number: 20050080242
    Abstract: The present invention provides a sensor and methods for determining kinase activity.
    Type: Application
    Filed: October 8, 2003
    Publication date: April 14, 2005
    Inventors: Barbara Imperiali, Melissa Shults
  • Fluorescence assay for kinase activity
    Publication number: 20050080243
    Abstract: The present invention provides a sensor and methods for determining kinase activity.
    Type: Application
    Filed: April 6, 2004
    Publication date: April 14, 2005
    Inventors: Barbara Imperiali, Melissa Shults
  • Lanthanide binding tags
    Publication number: 20030228622
    Abstract: The present invention provides lanthanide binding tags (LBT) that selectively complex trivalent lanthanide (Ln) ions and afford stable complexes with desirable physical properties, including at least one of fluorescence and anomalous x-ray scattering.
    Type: Application
    Filed: September 5, 2002
    Publication date: December 11, 2003
    Inventors: Barbara Imperiali, Karen N. Allen, Katherine J. Franz
  • Method for screening peptides for metal coordinating properties and fluorescent chemosensors derived therefrom
    Patent number: 6083758
    Abstract: Methods for identifying polypeptides which coordinate to select metals, chemosensors comprising polypeptides which coordinate to select metals and methods for selectively detecting the presence of metals using these chemosensors are disclosed.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: July 4, 2000
    Assignee: California Institute of Technology
    Inventors: Barbara Imperiali, Grant K. Walkup
  • Inhibitors of oligosaccharyl transferase
    Patent number: 5994502
    Abstract: The present invention provides novel inhibitors of oligosaccharyl transferase, methods for producing Glc.sub.3 Man.sub.9 (GlcNAc).sub.2 --P--P--Dol, and methods for producing glycopeptides.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: November 30, 1999
    Inventors: Barbara Imperiali, Jeffrey R. Spencer, Tamara L. Hendrickson
  • Peptidyl fluorescent chemosensor for divalent zinc
    Patent number: 5928955
    Abstract: The present invention provides a selective fluorescent chemosensor, sensitive to nanomolar concentrations of zinc(II) and selective for this ion over Na.sup.+, Mg.sup.2+, Co.sup.2+.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: July 27, 1999
    Assignee: California Institute of Technology
    Inventors: Barbara Imperiali, Grant K. Walkup
  • Inhibitors of oligosaccharyl transferase
    Patent number: 5721338
    Abstract: The present invention provides novel inhibitors of oligosaccharyl transferase, methods for producing Glc.sub.3 Man.sub.9 (GlcNAc).sub.2 -P-P-Dol, and methods for producing glycopeptides.
    Type: Grant
    Filed: December 7, 1995
    Date of Patent: February 24, 1998
    Assignee: California Institute of Technology
    Inventors: Barbara Imperiali, Jeffrey R. Spencer, Tamara L. Hendrickson