Patents by Inventor Barbara MELILLI

Barbara MELILLI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMICALLY AND PHYSICALLY STABLE TOPICAL OPHTHALMIC NEPAFENAC-BASED FORMULATIONS
    Publication number: 20220096404
    Abstract: Topical ophthalmic Nepafenac-based formulations, which are particularly stable from both chemical and physical points of view, are provided.
    Type: Application
    Filed: January 14, 2020
    Publication date: March 31, 2022
    Inventors: Danilo ALEO, Maria Grazia SAITA, Barbara MELILLI, Sergio MANGIAFICO, Melina CRO
  • OPHTHALMIC COMPOSITION COMPRISING PVP-I
    Publication number: 20200000714
    Abstract: An ophthalmic composition includes Povidone-iodine (PVP-I) at a concentration of between 0.2%-1.0% (w/w). The ophthalmic composition has an aqueous phase and an oil phase, the oil phase constituting medium-chain triglycerides and the oil phase constituting less than 3% of the total weight of the composition.
    Type: Application
    Filed: February 17, 2017
    Publication date: January 2, 2020
    Inventors: Danilo ALEO, Melina CRO, Sergio MANGIAFICO, Barbara MELILLI, Maria Grazia SAITA
  • Aqueous ophthalmic formulations based on azithromycin
    Patent number: 10342816
    Abstract: The invention concerns topical ophthalmic preparations in the form of eye-drops in aqueous solution, containing azithromycin (or a pharmacologically acceptable salt thereof) as active ingredient, wherein the azithromycin is solubilized and stabilized by means of ?-cyclodextrins, and in particular by means of the ?-cyclodextrin called sulfobutyl ether ?-cyclodextrin (SBE-?-CD). The proposed preparations have a remarkably high stability, both physical and chemical, which enables its storage at room temperature for the envisaged period of validity for a commercial pharmaceutical product.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: July 9, 2019
    Assignee: MEDIVIS S.R.L.
    Inventors: Danilo Aleo, Maria Grazia Antonietta Saita, Barbara Melilli, Sergio Mangiafico, Melina Cro
  • AQUEOUS OPHTHALMIC FORMULATIONS BASED ON AZITHROMYCIN
    Publication number: 20160074426
    Abstract: The invention concerns topical ophthalmic preparations in the form of eye-drops in aqueous solution, containing azithromycin (or a pharmacologically acceptable salt thereof) as active ingredient, wherein the azithromycin is solubilized and stabilized by means of ?-cyclodextrins, and in particular by means of the ?-cyclodextrin called sulfobutyl ether ?-cyclodextrin (SBE-?-CD). The proposed preparations have a remarkably high stability, both physical and chemical, which enables its storage at room temperature for the envisaged period of validity for a commercial pharmaceutical product.
    Type: Application
    Filed: May 6, 2014
    Publication date: March 17, 2016
    Applicant: MEDIVIS S.R.L.
    Inventors: Danilo ALEO, Maria Grazia Antonietta SAITA, Barbara MELILLI, Sergio MANGIAFICO, Melina CRO