Patents by Inventor Barbara Murza

Barbara Murza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
    Patent number: 7235404
    Abstract: A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and release hemoglobin and a ligand to form a stable chromogen with the hemoglobin. The lytic reagent composition has a pH in a range of 3 to 10. The lytic reagent composition can also include a second quaternary ammonium surfactant. The ligand can be malic acid, malonic acid, ethylene diamine, N,N-diethylethylene diamine, N,N?-diethylethylene diamine, diethylene triamine, tetraethylene pentamine, 1,6-hexanediamine, 1,3-pentanediamine, 2-methylpentamethylenediamine, 1,2-diaminocyclohexane, 4-aminoacetophenone, bis-hexamethylenetriamine, pyridazine, or 3,6-dihyroxypyridazine.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: June 26, 2007
    Assignee: Beckman Coulter, Inc.
    Inventors: Russell F. Lang, Dennisse Parra-Diaz, Luisa Oramas, Barbara Murza, Susana Maldonado
  • Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
    Publication number: 20060263889
    Abstract: A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and release hemoglobin and a ligand to form a stable chromogen with the hemoglobin. The lytic reagent composition has a pH in a range of 3 to 10. The lytic reagent composition can also include a second quaternary ammonium surfactant. The ligand can be malic acid, malonic acid, ethylene diamine, N,N-diethylethylene diamine, N,N?-diethylethylene diamine, diethylene triamine, tetraethylene pentamine, 1,6-hexanediamine, 1,3-pentanediamine, 2-methylpentamethylenediamine, 1,2-diaminocyclohexane, 4-aminoacetophenone, bis-hexamethylenetriamine, pyridazine, or 3,6-dihyroxypyridazine.
    Type: Application
    Filed: May 4, 2005
    Publication date: November 23, 2006
    Applicant: Beckman Coulter, Inc.
    Inventors: Russell Lang, Dennisse Parra-Diaz, Luisa Oramas, Barbara Murza, Susana Maldonado