Patents by Inventor Barbara S. Briggs

Barbara S. Briggs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme from microbial source: phthalyl amidase
    Patent number: 5607850
    Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides said phthalyl amidase, means for producing it by culturing the natural organism from which the activity was identified, and methods for using said phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: March 4, 1997
    Assignee: Eli Lilly and Company
    Inventors: Barbara S. Briggs, Milton J. Zmijewski, Jr.
  • Process for preparation of benzo[B]thiophene glucuronides
    Patent number: 5563054
    Abstract: The present invention provides a biotransformation process for preparing a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen or a .beta.-glucuronide group of the formula ##STR2## provided at least one of R.sub.1 and R.sub.2 is a .beta.-glucuronide group.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: October 8, 1996
    Assignee: Eli Lilly and Company
    Inventors: Barbara S. Briggs, Milton J. Zmijewski, Jr.
  • Phthalyl amidase-producing Xanthobacter agilis
    Patent number: 5532161
    Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides 2 phthalyl amidase, 2 method for producing it by culturing the natural organism from which the activity was identified, and methods for using the phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides. The ezyme is isolated from Xanthobacter agilis.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: July 2, 1996
    Assignee: Eli Lilly and Company
    Inventors: Barbara S. Briggs, Milton J. Zmijewski, Jr.
  • Removal of phthalyl groups from amides and esters using an amidase isolated from Xanthobacter Agilis
    Patent number: 5532149
    Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides a phthalyl amidase, a method for producing it by culturing the natural organism from which the activity was identified, and methods for using the phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides. The enzyme is isolated from Xanthobacter agilis.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: July 2, 1996
    Assignee: Eli Lilly and Company
    Inventors: Barbara S. Briggs, Milton J. Zmijewski, Jr.
  • Enzyme from microbial source: phthalyl amidase
    Patent number: 5445959
    Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides said phthalyl amidase, means for producing it by culturing the natural organism from which the activity was identified, and methods for using said phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides.
    Type: Grant
    Filed: July 15, 1994
    Date of Patent: August 29, 1995
    Assignee: Eli Lilly and Company
    Inventors: Barbara S. Briggs, Milton J. Zmijewski, Jr.