Patents by Inventor Barbara Slusher

Barbara Slusher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE USING PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS
    Publication number: 20170224709
    Abstract: Methods and compounds are disclosed for treating inflammatory bowel disease (IBD) by using Prostate Specific Membrane Antigen (PSMA) inhibitors.
    Type: Application
    Filed: August 6, 2015
    Publication date: August 10, 2017
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: BARBARA SLUSHER, RANA RAIS, XUHANG LI
  • Thiolactones
    Publication number: 20080004334
    Abstract: This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogenesis, effecting a TGF-? activity or a neuronal activity, and treating a glutamate abnormality, a compulsive disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma.
    Type: Application
    Filed: July 30, 2007
    Publication date: January 3, 2008
    Inventors: Barbara Slusher, Takashi Tsukamoto
  • Methods Of Administering Water-Soluble Prodrugs Of Propofol For Extended Sedation
    Publication number: 20070202158
    Abstract: A method of administering a prodrug of propofol, preferably O-phosphonooxymethyl propofol disodium salt, comprises the oral, intragastric, or intraintestinal administration of the prodrug in amounts sufficient to induce or maintain a generalized anesthetized state, a conscious sedated state, or to treat insomnia, anxiety, nausea, vomiting, pruritus, epilepsy, and a range of pain syndromes and other medical conditions.
    Type: Application
    Filed: December 17, 2004
    Publication date: August 30, 2007
    Applicant: MGI GP, Inc.
    Inventors: Barbara Slusher, Krystyna Wozniak
  • Thiolactones
    Publication number: 20070037798
    Abstract: This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogenesis, effecting a TGF-? activity or a neuronal activity, and treating a glutamate abnormality, a compulsive disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma.
    Type: Application
    Filed: October 2, 2006
    Publication date: February 15, 2007
    Inventors: Barbara Slusher, Takashi Tsukamoto
  • Thiol-based NAALADase inhibitors
    Publication number: 20060135812
    Abstract: This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-? activity, inhibiting angiogenesis and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
    Type: Application
    Filed: January 5, 2006
    Publication date: June 22, 2006
    Inventors: Takashi Tsukamoto, Pavel Majer, Doris Stoermer, Barbara Slusher
  • Benzenedicarboxylic acid derivatives
    Publication number: 20050171065
    Abstract: New benzenedicarboxylic acid derivative compounds; pharmaceutical compositions, diagnostic methods, and diagnostic kits that include those compounds; and methods of using those compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-? activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers, and glaucoma.
    Type: Application
    Filed: February 7, 2005
    Publication date: August 4, 2005
    Inventors: Paul Jackson, Takashi Tsukamoto, Barbara Slusher, Eric Wang
  • Thiol-based NAALADase inhibitors
    Publication number: 20050085503
    Abstract: This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-? activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Inventors: Takashi Tsukamoto, Pavel Majer, Doris Stoermer, Barbara Slusher
  • Naaladase inhibitors for treating huntington's disease
    Publication number: 20050080139
    Abstract: This invention relates to a pharmaceutical composition and a method for treating Huntington's disease using NAAL-ADase inhibitors.
    Type: Application
    Filed: December 27, 2002
    Publication date: April 14, 2005
    Inventors: Barbara Slusher, Krystyna Wozniak
  • Thiolactones
    Publication number: 20050004203
    Abstract: This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogenesis, effecting a TGF-? activity or a neuronal activity, and treating a glutamate abnormality, a compulsive disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma.
    Type: Application
    Filed: March 3, 2004
    Publication date: January 6, 2005
    Inventors: Barbara Slusher, Takashi Tsukamoto