Patents by Inventor Barbara Spengler

Barbara Spengler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120071501
    Abstract: The present invention relates to extracts from Cimicifuga species and particularly from Cimicifuga racemosa, which are suited for producing a ready-formulated drug for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The extracts in accordance with the invention are moreover suited for the treatment and/or prophylaxis of post-menopausal urinary bladder infections. They are furthermore indicated for the treatment of benign and malignant prostate hyperplasies.
    Type: Application
    Filed: November 28, 2011
    Publication date: March 22, 2012
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Volker Christoffel, Barbara Spengler
  • Publication number: 20080300230
    Abstract: The present invention relates to extracts from Cimicifuga species and particularly from Cimicifuga racemosa, which are suited for producing a ready-formulated drug for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The extracts in accordance with the invention are moreover suited for the treatment and/or prophylaxis of post-menopausal urinary bladder infections. They are furthermore indicated for the treatment of benign and malignant prostate hyperplasies.
    Type: Application
    Filed: August 14, 2008
    Publication date: December 4, 2008
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Volker Christoffel, Barbara Spengler
  • Patent number: 7413754
    Abstract: The present invention relates to extracts from Cimicifuga species and particularly from Cimicifuga racemosa, which are suited for producing a ready-formulated drug for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The extracts in accordance with the invention are moreover suited for the treatment and/or prophylaxis of post-menopausal urinary bladder infections. They are furthermore indicated for the treatment of benign and malignant prostate hyperplasies.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: August 19, 2008
    Assignee: Bionorica AG
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Volker Christoffel, Barbara Spengler
  • Publication number: 20070122503
    Abstract: The present invention relates to the use of extracts from Cimicifuga racemosa, and of tectorigenin as an estrogen-type, organoselective medicament for the selective treatment and/or prophylaxis of cardiovascular diseases, atherosclerosis, osteoporosis and climacteric disorders, e.g. for preventing or alleviating hot flushes. Uterotrophic effects are practically not observed.
    Type: Application
    Filed: December 29, 2006
    Publication date: May 31, 2007
    Applicant: BIONORICA ARZNEIMITTEL GMBH
    Inventors: WOLFGANG WUTTKE, Hubertus Jarry, Volker Christoffel, Barbara Spengler, Michael Popp
  • Publication number: 20050220900
    Abstract: The present invention relates to the use of phytoestrogen-containing extracts that selectively modulate estrogen receptor beta (ER-beta) without producing any uterotropic effect, for the treatment of clinical situations and pathophysiological conditions that are selected from the group consisting of: Obesity and thereby to possibly influence the metabolic syndrome, particularly hypertension, asterosclerosis, cardiac infarct, hyperandrogenemia; Menopausal continence disorders; Menopausal heat surges associated with hyperstimulation of the hypothalamic gonadotropin releasing hormone pulse generator; steroid hormonal synthesis disorder, particularly that of progesterone synthesis of the human corpus luteum, resulting in luteal insuffeciency; Alzheimer's disease associated with elevated expression of estrogen receptor beta in hippocampal neurons.
    Type: Application
    Filed: February 10, 2003
    Publication date: October 6, 2005
    Inventors: Michael Popp, Wolfgang Wuttke, Hubertus Jarry, Volker Christoffel, Barbara Spengler
  • Publication number: 20050037100
    Abstract: The present invention relates to the use of extracts from Iridaceae and from Cimicifuga racemosa, and of tectorigenin as an estrogen-type, organoselective medicament for the selective treatment and/or prophylaxis of cardiovascular diseases, in particular atherosclerose, osteoporose and climacteric disorders, e.g. for preventing or alleviating hot flushes. Uterotrophic effects are practically not observed.
    Type: Application
    Filed: September 27, 2004
    Publication date: February 17, 2005
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Volker Christoffel, Barbara Spengler, Michael Popp
  • Publication number: 20050019437
    Abstract: The present invention relates to extracts from Cimicifuga species and particularly from Cimicifuga racemosa, which are suited for producing a ready-formulated drug for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The extracts in accordance with the invention are moreover suited for the treatment and/or prophylaxis of post-menopausal urinary bladder infections. They are furthermore indicated for the treatment of benign and malignant prostate hyperplasies.
    Type: Application
    Filed: September 16, 2002
    Publication date: January 27, 2005
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Christoffel Volker, Barbara Spengler
  • Publication number: 20040176310
    Abstract: The present invention relates to extracts from the lridaceae plant Belamcanda chinensis for producing a ready-formulated medicament suited for the selective treatment and/or prophylaxis of sexual hormone-related disorders of the uro-genital tract. The inventive extracts are moreover suited for the treatment and/or prophylaxis of post-menopausal bladder infections and of urinary incontinence. The are moreover indicated for the treatment of benign and malignant prostate hyperplasies. It was moreover found that the ingredient tectorigenin as well as its glycosides, isolated from Belamcanda chinensis, essentially has the same effects as the whole extract.
    Type: Application
    Filed: May 3, 2004
    Publication date: September 9, 2004
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Michael Popp, Volker Christoffel, Barbara Spengler
  • Publication number: 20040138297
    Abstract: The present invention relates to a prolactin lowering drug containing at least one bicyclic diterpene of the labdane type.
    Type: Application
    Filed: October 2, 2003
    Publication date: July 15, 2004
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Michael Popp, Volker Christoffel, Barbara Spengler
  • Patent number: 6635672
    Abstract: The present invention relates to a prolactin lowering drug containing at least one bicyclic diterpene of the labdane or clerodane type: wherein R1=H, C1 to C3 alkyl or C1 to C3 acyl.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: October 21, 2003
    Assignee: Bionorica AG
    Inventors: Wolfgang Wuttke, Hubertus Jarry, Michael Popp, Volker Christoffel, Barbara Spengler