Patents by Inventor Barbara Steiner

Barbara Steiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR BIOTRANSFORMATION OF TRICHOTHECENES
    Publication number: 20220298521
    Abstract: The present invention relates to a novel method for detoxification of trichothecene contaminated material. More specifically the present invention pertains to a method for biotransformation of a trichothecene by contacting material contaminated with trichothecenes with an exogenous non-animal glutathione-S-transferase (GST) having substrate specificity for the epoxide ring of the trichothecene. The invention further relates to recombinant GSTs and transgenic plants and animals expressing said GSTs.
    Type: Application
    Filed: June 19, 2020
    Publication date: September 22, 2022
    Inventors: Martin Siller, Gerhard Adam, Maria Doppier, Rainer Schuhmacher, Karl Kugler, Klaus F.X. Mayer, Gerlinde Wiesenberger, Herbert Michlmayr, Wolfgang Schweiger, Manuel Hofer, Hermann Bürstmayr, Barbara Steiner
  • Novel Tools for the Diagnosis and Treatment of Alzheimer's Disease
    Publication number: 20090162336
    Abstract: The invention relates to epitopes of the tau protein which are specifically occurring in a phosphorylated state in tau protein from Alzheimer paired helical filaments, to protein kinases which are responsible for the phosphorylation of the amino acids of the tau protein giving rise to said epitopes, and to antibodies specific for said epitopes. The invention further relates to pharmaceutical compositions for the treatment or prevention of Alzheimer's disease, to diagnostic compositions and methods for the detection of Alzheimer's disease and to the use of said epitopes for the generation of antibodies specifically detecting Alzheimer tau protein. Additionally, the invention relates to methods for testing drugs effective in dissolving Alzheimer paired helical filaments or preventing the formation thereof.
    Type: Application
    Filed: August 4, 2008
    Publication date: June 25, 2009
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNGDER WISSENSCHAFTEN, E.V.
    Inventors: Eva-Marie Mandelkow, Eckhard Mandelkow, Birgit Lichtenberg-Kraag, Jacek Biernat, Gerard Drewes, Barbara Steiner
  • Tools for the diagnosis and treatment of Alzheimer's disease
    Patent number: 7408027
    Abstract: The invention relates to epitopes of the tau protein which are specifically occurring in a phosphorylated state in tau protein from Alzheimer paired helical filaments, to protein kinases which are responsible for the phosphorylation of the amino acids of the tau protein giving rise to said epitopes, and to antibodies specific for said epitopes. The invention further relates to pharmaceutical compositions for the treatment or prevention of Alzheimer's disease, to diagnostic compositions and methods for the detection of Alzheimer's disease and to the use of said epitopes for the generation of antibodies specifically detecting Alzheimer tau protein. Additionally, the invention relates to methods for testing drugs effective in dissolving Alzheimer paired helical filaments or preventing the formation thereof.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: August 5, 2008
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenchaften
    Inventors: Eva-Maria Mandelkow, Eckhard Mandelkow, Birgit Lichtenberg-Kraag, Jacek Biernat, Gerard Drewes, Barbara Steiner
  • Tools for the diagnosis and treatment of Alzheimer's disease
    Patent number: 7176290
    Abstract: The present invention relates to phosphorylated tau protein epitopes associated with Alzheimer's disease, to protein kinases responsible for tau protein epitope phosphorylation, and to antibodies specific for the tau epitopes. Additionally, the present invention relates to pharmaceutical compositions, methods for detection, and methods of testing drugs effective in dissolving paired helical filaments associated with Alzheimer's disease.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: February 13, 2007
    Assignee: Max-Planck-Gesellschaft zur Forderungder Wissenshaften, E.V.
    Inventors: Eva-Marie Mandelkow, Eckhard Mandelkow, Birgit Lichtenberg-Kraag, Jacek Biernat, Gerard Drewes, Barbara Steiner
  • Novel tools for the diagnosis and treatment of Alzheimer's disease
    Publication number: 20020188106
    Abstract: The invention relates to epitopes of the tau protein which are specifically occurring in a phosphorylated state in tau protein from Alzheimer paired helical filaments, to protein kinases which are responsible for the phosphorylation of the amino acids of the tau protein giving rise to said epitopes, and to antibodies specific for said epitopes. The invention further relates to pharmaceutical compositions for the treatment or prevention of Alzheimer's disease, to diagnostic compositions and methods for the detection of Alzheimer's disease and to the use of said epitopes for the generation of antibodies specifically detecting Alzheimer tau protein. Additionally, the invention relates to methods for testing drugs effective in dissolving Alzheimer paired helical filaments or preventing the formation thereof.
    Type: Application
    Filed: February 4, 2002
    Publication date: December 12, 2002
    Applicant: Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften, E.V.
    Inventors: Eva-Marie Mandelkow, Eckhard Mandelkow, Birgit Lichtenberg-Kragg, Jacek Biernat, Gerard Drewes, Barbara Steiner
  • Method of screening for compounds that dissolve paired helical filaments
    Patent number: 6200768
    Abstract: The invention relates to epitopes of the protein which are specifically occurring in a phosphorylated state in tau protein from Alzheimer paired helical filaments, to protein kinases which are responsible for the phosphorylation of the amino acids of the tau protein giving rise to said epitopes, and to antibodies specific for said epitopes. The invention further relates to pharmaceutical compositions for the treatment or prevention of Alzheimer's disease, to diagnostic compositions and methods for the detection of Alzheimer's disease and to the use of said epitopes for the generation of antibodies specifically detecting Alzheimer tau protein. Additionally, the invention relates to methods for testing drugs effective in dissolving Alzheimer paired helical filaments or preventing the formation thereof.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: March 13, 2001
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften
    Inventors: Eva-Maria Mandelkow, Eckhard Mandelkow, Birgit Lichtenberg-Kraag, Jacek Biernat, Gerard Drewes, Barbara Steiner