Patents by Inventor Barbara Stella

Barbara Stella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE PREPARATION OF HYBRID POLYMERIC NANOPARTICLES FOR THE RELEASE OF OLIGONUCLEOTIDE DRUGS IN PHARMACOLOGICAL THERAPIES FOR REGENERATIVE, CURATIVE, AND PREVENTIVE PURPOSES
    Publication number: 20250057779
    Abstract: Hybrid nanoparticles consisting of a polymeric component encapsulating cationic liposomes and/or lipoplexes comprising a cationic lipid and a helper lipid are described, wherein the polymeric component constitutes at least the 80% by weight with respect to the total material constituting the nanoparticles.
    Type: Application
    Filed: December 22, 2022
    Publication date: February 20, 2025
    Applicants: POLITECNICO DI TORINO (75%), UNIVERSITA' DEGLI STUDI DI TORINO (25%)
    Inventors: Valeria Chiono, Clara Mattu, Letizia Nicoletti, Camilla Paoletti, Silvia Maria Angela Arpicco, Barbara Stella
  • Nanoparticles of therapeutic agents having low water solubility
    Patent number: 8962552
    Abstract: The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.
    Type: Grant
    Filed: November 27, 2008
    Date of Patent: February 24, 2015
    Assignees: Centre Nationale de Recherche Scientifique, Universite Paris SU XI
    Inventors: Patrick Couvreur, Harivardhan Reddy Lakkireddy, Franco Dosio, Barbara Stella, Luigi Cattel
  • Nanoparticle derivatives of gemcitabine
    Patent number: 8044034
    Abstract: The use of squalenic acid or a derivative thereof in formulating at least one polar active principle with a molecular weight of 100 Da or more, in the form of nanoparticles, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: October 25, 2011
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite Paris-Sud
    Inventors: Patrick Couvreur, Barbara Stella, Luigi Cattel, Flavio Rocco, Jack-Michel Renoir, Veronique Rosilio
  • NANOPARTICLES OF THERAPEUTIC AGENTS HAVING LOW WATER SOLUBILITY
    Publication number: 20100305030
    Abstract: The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.
    Type: Application
    Filed: November 27, 2008
    Publication date: December 2, 2010
    Applicants: Centre National De La Recherche Scientifique, Universite Paris Sud XI
    Inventors: Patrick Couvreur, Harivardhan Reddy Lakkireddy, Franco Dosio, Barbara Stella, Luigi Cattel
  • NANOPARTICLE DERIVATIVES OF GEMCITABINE
    Publication number: 20100160249
    Abstract: The use of squalenic acid or a derivative thereof in formulating at least one polar active principle with a molecular weight of 100 Da or more, in the form of nanoparticles, and pharmaceutical compositions thereof.
    Type: Application
    Filed: March 4, 2010
    Publication date: June 24, 2010
    Applicants: Centre National De La Recherche Scientifique, Universite Paris-Sud
    Inventors: Patrick Couvreur, Barbara Stella, Luigi Cattel, Flavio Rocco, Jack-Michel Renoir, Véronique Rosilio
  • Gemcitabine derivatives nanoparticles
    Patent number: 7704972
    Abstract: The invention concerns a 2?,2?-difluoro-2?-deoxycytidine derivative of general formula (I), wherein: R1, R2 and R3, identical or different, represent independently of one another, a hydrogen atom or an at least C18 hydrocarbon acyl radical and of such conformation that it is capable of providing the compound of general formula (I), a compacted form in a polar solvent medium, at least one of groups R1, R2 and R3 being other than a hydrogen atom.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: April 27, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Paris-SUD
    Inventors: Patrick Couvreur, Barbara Stella, Luigi Cattel, Flavio Rocco, Jack-Michel Renoir, Véronique Rosilio
  • Gemcitabine derivatives nanoparticles
    Publication number: 20090130214
    Abstract: The invention concerns a 2?,2?-difluoro-2?-deoxycytidine derivative of general formula (I), wherein: R1, R2 and R3, identical or different, represent independently of one another, a hydrogen atom or an at least C18 hydrocarbon acyl radical and of such conformation that it is capable of providing the compound of general formula (I), a compacted form in a polar solvent medium, at least one of groups R1, R2 and R3 being other than a hydrogen atom.
    Type: Application
    Filed: June 23, 2005
    Publication date: May 21, 2009
    Inventors: Patrick Couvreur, Barbara Stella, Luigi Cattel, Flavio Rocco, Jack-Michel Renoir, Veronique Rosilio