Patents by Inventor Barbra Sasu

Barbra Sasu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTORS TARGETING CD70
    Publication number: 20230041456
    Abstract: The disclosure provides CARs (CARs) that specifically bind to CD70. The disclosure further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The disclosure further relates to therapeutic methods for use of these CARs and engineered immune cells comprising these CARs for the treatment of a condition associated with malignant cells expressing CD70 (e.g., cancer).
    Type: Application
    Filed: June 17, 2022
    Publication date: February 9, 2023
    Inventors: Surabhi SRIVATSA SRINIVASAN, Niranjana NAGARAJAN, Siler PANOWSKI, Yoon PARK, Tao SAI, Barbra SASU, Thomas VAN BLARCOM, Mathilde DUSSEAUX, Roman GALETTO
  • Ferroportin antibodies and methods of use
    Patent number: 9688759
    Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 27, 2017
    Assignee: Amgen, Inc.
    Inventors: Tara Arvedson, Gregory Dyas, James B. Rottman, Barbra Sasu, Xiao-juan Bi, Grace Ki Jeong Lee, Jackie Z. Sheng
  • FERROPORTIN ANTIBODIES AND METHODS OF USE
    Publication number: 20160083470
    Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 24, 2016
    Applicant: AMGEN INC.
    Inventors: Tara ARVEDSON, Gregory DYAS, James B. ROTTMAN, Barbra SASU, Xiao-juan BI, Grace Ki Jeong LEE, Jackie Z. SHENG
  • Ferroportin antibodies and methods of use
    Patent number: 9175078
    Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: November 3, 2015
    Assignee: AMGEN INC.
    Inventors: Tara Arvedson, Gregory Dyas, James B. Rottman, Barbra Sasu, Xiao-juan Bi, Grace Ki Jeong Lee, Jackie Z. Sheng
  • HEPCIDIN, HEPCIDIN ANTAGONISTS AND METHODS OF USE
    Publication number: 20140286953
    Abstract: The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provide are methods of treated hepcidin-related disorders.
    Type: Application
    Filed: December 11, 2013
    Publication date: September 25, 2014
    Applicant: Amgen Inc.
    Inventors: Barbra Sasu, Mitsuru Haniu, Thomas Charles Boone, Xiao-juan Bi, Grace Ki Jeong Lee, Tara Arvedson, Aaron George Winters, Keegan Cooke, Jackie Z. Sheng
  • Hepcidin, hepcidin antagonists and methods of use
    Patent number: 8629250
    Abstract: The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provide are methods of treated hepcidin-related disorders.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: January 14, 2014
    Assignee: Amgen Inc.
    Inventors: Barbra Sasu, Mitsuru Haniu, Thomas Charles Boone, Xiao-juan Bi, Grace Ki Jeong Lee, Tara Arvedson, Aaron George Winters, Keegan Cooke, Jackie Z. Sheng
  • METHOD OF DETECTING AND/OR MEASURING HEPCIDIN IN A SAMPLE
    Publication number: 20110312888
    Abstract: Methods of isolating and/or analyzing hepcidin by mass spectrometry and methods of quantifying hepcidin are disclosed.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 22, 2011
    Applicant: AMGEN INC.
    Inventors: Hongyan Li, Alan Breau, Barbra Sasu
  • FERROPORTIN ANTIBODIES AND METHODS OF USE
    Publication number: 20110274691
    Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.
    Type: Application
    Filed: January 23, 2009
    Publication date: November 10, 2011
    Inventors: Tara Arvedson, James Rottman, Barbra Sasu, Gregory Dyas
  • Method of detecting and/or measuring hepcidin in a sample
    Publication number: 20090173876
    Abstract: Methods of isolating and/or analyzing hepcidin by mass spectrometry and methods of quantifying hepcidin are disclosed.
    Type: Application
    Filed: July 20, 2007
    Publication date: July 9, 2009
    Applicant: AMGEN INC.
    Inventors: Hongyan Li, Alan Breau, Barbra Sasu
  • HEPCIDIN, HEPCIDIN ANTAGONISTS AND METHODS OF USE
    Publication number: 20080213277
    Abstract: The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provide are methods of treated hepcidin-related disorders.
    Type: Application
    Filed: January 30, 2008
    Publication date: September 4, 2008
    Applicant: AMGEN INC.
    Inventors: Barbra Sasu, Mitsuru Hainu, Thomas Charles Boone, Xiao-Juan Bi, Ki Jeong Lee, Tara Arvedson, Aaron Winters, Keegan Cooke, Zeqi Sheng