Patents by Inventor Barend Groen

Barend Groen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enantioselective preparation of s-2R.sub.1,2R.sub.2 -1,3-dioxolane-4-methanol and derivatives thereof
    Patent number: 5182209
    Abstract: Process for the enantioselective conversion of an enantiomer mixture of 2R.sub.1,2R.sub.2 -1,3-dioxolane-4-methanol including the following steps: combining the enantioselective enzyme, PQQ-dependent alcohol dehydrogenase with an enantiomer mixture of 2R.sub.1, 2R.sub.2 -1,3-dioxolane-4-methanol of the formula: ##STR1## where R.sub.1 and R.sub.2 independently are selected from the group consisting of hydrogen, an optionally branched alkyl group, an aryl, and R.sub.1 and R.sub.2 with the carbon atom to which they are attached being an optionally substituted carbocyclic ring, the combination of ingredients producing 2R.sub.1,2R.sub.2 -3-dioxolane-4-methanol enriched in the S-enantiomer i.e. S-2R.sub.1,2R.sub.2 -1,3-dioxolane-4-methanol.
    Type: Grant
    Filed: June 22, 1990
    Date of Patent: January 26, 1993
    Assignee: DSM N.V.
    Inventors: Arie Geerlof, Barend Groen, Johannis A. Duine