Patents by Inventor Bari A. Barwis

Bari A. Barwis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides peptide analogs peptidomimetics and other small molecules useful for inhibiting the activity of ribonucleotide reductase
    Patent number: 6030942
    Abstract: The invention relates to compositions which are useful for inhibiting ribonucleotide reductase enzymes, including the mammalian ribonucleotide reductase enzyme. The compositions include, but are not limited to, linear peptides, cyclic peptides, peptide analogs, and peptidomimetics. Methods of using the compositions of the invention to treat cancer and viral and bacterial infections are disclosed.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: February 29, 2000
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Barry S. Cooperman, Ralph F. Hirschmann, Amos B. Smith, III, Paul Laub, Setsuya Sasho, Paul A. Sprengeler, Bari A. Barwis, Alison Fisher, Shrikumar Nair