Patents by Inventor Barnaba Krochmal

Barnaba Krochmal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7915423
    Abstract: Crystalline pantoprazole sodium Forms II, IV, V, VI, VIII, IX, X, XI, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX and XX; pantoprazole sodium solvates containing water, acetone, butanol, methylethylketone, dimethylcarbonate, propanol and 2-methylpropanol; and amorphous pantoprazole sodium are disclosed.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: March 29, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Nina Finkelstein, Barnaba Krochmal, Shlomit Wizel, Viviana Braude
  • Patent number: 7671071
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: March 2, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Publication number: 20090149497
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is anhydrous, but can be crystallized as a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: September 9, 2008
    Publication date: June 11, 2009
    Inventors: Ben-Zion DOLITZKY, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross
  • Patent number: 7507829
    Abstract: Crystalline pantoprazole sodium Forms II, IV, V, VI, VIII, IX, X, XI, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX and XX; pantoprazole sodium solvates containing water, acetone, butanol, methylethylketone, dimethylcarbonate, propanol and 2-methylpropanol; and amorphous pantoprazole sodium are disclosed.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: March 24, 2009
    Assignee: Teva Pharmaceuticals Industries, Ltd
    Inventors: Nina Finkelstein, Barnaba Krochmal, Shlomit Wizel, Viviana Braude
  • Publication number: 20090054486
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: September 11, 2008
    Publication date: February 26, 2009
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Publication number: 20090012121
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: September 9, 2008
    Publication date: January 8, 2009
    Inventors: Ben-Zion DOLITZKY, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross
  • Publication number: 20080132707
    Abstract: Crystalline pantoprazole sodium Forms II, IV, V, VI, VIII, IX, X, XI, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX and XX; pantoprazole sodium solvates containing water, acetone, butanol, methylethylketone, dimethylcarbonate, propanol and 2-methylpropanol; and amorphous pantoprazole sodium are disclosed.
    Type: Application
    Filed: July 27, 2007
    Publication date: June 5, 2008
    Inventors: Nina Finkelstein, Barnaba Krochmal, Shlomit Wizel, Viviana Braude
  • Patent number: 7256195
    Abstract: The present invention is directed to the novel forms of risperidone, designated Form A, Form B and Form E. Methods for their preparation are also disclosed. The present invention also relates to processes for making risperidone. Pharmaceutical compositions containing the new forms of risperidone and methods of using them are also disclosed.
    Type: Grant
    Filed: September 23, 2003
    Date of Patent: August 14, 2007
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime
  • Publication number: 20060217557
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: October 3, 2005
    Publication date: September 28, 2006
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Publication number: 20060111571
    Abstract: The present invention provides tadalafil crystal forms II, III, IV, VI, VII, and VIII, and processes for preparing these forms. The present invention also provides processes for preparing tadalafil forms I and V.
    Type: Application
    Filed: November 2, 2005
    Publication date: May 25, 2006
    Inventors: Shlomit Wizel, Barnaba Krochmal, Ariel Givant, Dov Diller
  • Publication number: 20040235904
    Abstract: The present invention relates to a polymorphic form (Form I) of pantoprazole and a processes of making same. Form I has a PXRD pattern with characteristic peaks at 6.6, 13.2, 13.7, 15.7, 23.1, and 23.4±0.2 °2&thgr; and a FTIR spectrum with characteristic bands at 1385, 1264, 1244, 1180, and 1027 at cm−1. The process of making Form I includes crystallizing pantaoprazole or forming slurry from amorphous pantoprazole. The present invention also relates to another polymorphic form (Form II) of pantoprazole and a process of making the same. Form II has a PXRD pattern with characteristic peaks at 5.8, 7.5, 9.3, 15.0, 22.0, and 22.6±0.2 °2&thgr; and a FTIR spectrum with characteristic bands at 3195, 1196, and 1584 at cm−1. The process of making Form II includes forming a slurry from amorphous pantoprazole.
    Type: Application
    Filed: March 12, 2004
    Publication date: November 25, 2004
    Inventors: Nina Finkelstein, Barnaba Krochmal, Shlomit Wizel
  • Publication number: 20040229905
    Abstract: The present invention is directed to the novel forms of risperidone, designated Form A, Form B and Form E. Methods for their preparation are also disclosed. The present invention also relates to processes for making risperidone. Pharmaceutical compositions containing the new forms of risperidone and methods of using them are also disclosed.
    Type: Application
    Filed: September 23, 2003
    Publication date: November 18, 2004
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime
  • Publication number: 20040177804
    Abstract: Crystalline pantoprazole sodium Forms II, IV, V, VI, VIII, IX, X, XI, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX and XX; pantoprazole sodium solvates containing water, acetone, butanol, methylethylketone, dimethylcarbonate, propanol and 2-methylpropanol; and amorphous pantoprazole sodium are disclosed.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 16, 2004
    Inventors: Nina Finkelstein, Barnaba Krochmal, Shlomit Wizel, Viviana Braude
  • Publication number: 20040167168
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: February 25, 2004
    Publication date: August 26, 2004
    Inventors: Ben-Zion Dolitzky, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross
  • Patent number: 6750341
    Abstract: The present invention is directed to the novel forms of risperidone, designated Form A, Form B and Form E. Methods for their preparation are also disclosed. The present invention also relates to processes for making risperidone. Pharmaceutical compositions containing the new forms of risperidone and methods of using them are also disclosed.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: June 15, 2004
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime
  • Publication number: 20040058955
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is anhydrous, but can be crystallized as a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: September 12, 2003
    Publication date: March 25, 2004
    Inventors: Ben-Zon Dolitzky, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross
  • Publication number: 20040044038
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: June 10, 2003
    Publication date: March 4, 2004
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Publication number: 20030158227
    Abstract: The present invention provides novel crystal forms of fexofenadine base and processes for their preparation. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: November 8, 2002
    Publication date: August 21, 2003
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel
  • Publication number: 20030021849
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: April 26, 2002
    Publication date: January 30, 2003
    Inventors: Ben-Zion Dolitzky, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross
  • Publication number: 20020177608
    Abstract: The present invention provides novel crystal forms of fexofenadine hydrochloride Forms V, VI and VIII through XV and processes for their preparation and preparation of amorphous form and other crystalline forms of fexofenadine hydrochloride. Forms XIV and XV are solvates of ethyl acetate, while Form IX is anhydrous, but can be crystallized as a solvate of MTBE or cyclohexane. The forms are useful for administration to humans and animals to alleviate symptoms caused by histamine. The present invention further provides pharmaceutical compositions of the new crystalline forms.
    Type: Application
    Filed: April 8, 2002
    Publication date: November 28, 2002
    Inventors: Ben-Zion Dolitzky, Shlomit Wizel, Barnaba Krochmal, Dov Diller, Irwin Gross