Patents by Inventor Barrett Ethan Steinberg

Barrett Ethan Steinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CFTR-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240093186
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.
    Type: Application
    Filed: September 20, 2023
    Publication date: March 21, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Aamir Mir, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, Robert James Citorik, William Edward Salomon, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • SERPINA-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240084334
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating alpha-1 antitrypsin deficiency (AATD) are described.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, William Edward Salomon, Robert James Citorik, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • PAH-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240082429
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating phenylketonuria (PKU) are described.
    Type: Application
    Filed: October 26, 2023
    Publication date: March 14, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, William Edward Salomon, Robert James Citorik, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240084333
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 14, 2024
    Inventors: Stephen Hoyt Cleaver, Barrett Ethan Steinberg, Jacob Rosenblum Rubens, Robert James Citorik, William Edward Salomon, Zi Jun Wang
  • NUCLEIC ACID MUTAGENESIS METHODS
    Publication number: 20240084348
    Abstract: The present disclosure relates to the manipulation of nucleic acids, and more particularly to systems and methods for nucleic acid mutagenesis.
    Type: Application
    Filed: February 16, 2023
    Publication date: March 14, 2024
    Inventor: Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240076638
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: March 7, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240076698
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 7, 2024
    Inventors: Stephen Hoyt Cleaver, Barrett Ethan Steinberg, Jacob Rosenblum Rubens, Robert James Citorik, William Edward Salomon, Zi Jun Wang
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240035049
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: July 19, 2023
    Publication date: February 1, 2024
    Inventors: Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, William Edward Salomon, Jacob Rosenblum Rubens, Robert James Citorik, Zi Jun Wang, Kyusik Kim, Randi Michelle Kotlar, Ananya Ray, Robert Charles Altshuler, Sandeep Kumar, Nathaniel Roquet, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240026324
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: January 25, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240018551
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 2, 2022
    Publication date: January 18, 2024
    Inventors: Stephen CLEAVER, Barrett Ethan STEINBERG, Jacob Rosenblum RUBENS, Robert James CITORIK, William Edward SALOMON, Zi Jun WANG
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240002886
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: January 4, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240002822
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: July 20, 2023
    Publication date: January 4, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • SYSTEMS AND METHODS FOR ONE-SHOT GUIDE RNA (ogRNA) TARGETING OF ENDOGENOUS AND SOURCE DNA
    Publication number: 20230416787
    Abstract: Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by cellular genomic or other sequences recognized by guide RNAs.
    Type: Application
    Filed: May 12, 2023
    Publication date: December 28, 2023
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Ari E. Friedland, Hariharan Jayaram, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20230348939
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: November 22, 2022
    Publication date: November 2, 2023
    Inventors: Anne Helen BOTHMER, Cecilia Giovanna Silvia COTTA-RAMUSINO, William Edward SALOMON, Jacob Rosenblum RUBENS, Robert James CITORIK, Zi Jun WANG, Kyusik KIM, Randi Michelle KOTLAR, Ananya RAY, Robert Charles ALTSHULER, Sandeep KUMAR, Nathaniel ROQUET, Barrett Ethan STEINBERG
  • EMULSION-BASED SCREENING METHODS
    Publication number: 20230313174
    Abstract: The present disclosure relates to compositions, systems and methods for analyzing activity of nucleases.
    Type: Application
    Filed: October 4, 2022
    Publication date: October 5, 2023
    Inventor: Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20230272430
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 1, 2022
    Publication date: August 31, 2023
    Inventors: Anne Helen BOTHMER, Cecilia Giovanna Silvia COTTA-RAMUSINO, William Edward SALOMON, Jacob Rosenblum RUBENS, Robert James CITORIK, Zi Jun WANG, Kyusik KIM, Randi Michelle KOTLAR, Ananya RAY, Robert Charles ALTSHULER, Sandeep KUMAR, Nathaniel ROQUET, Barrett Ethan STEINBERG
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20230242899
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 1, 2022
    Publication date: August 3, 2023
    Inventors: Barrett Ethan STEINBERG, Anne Helen BOTHMER, William Edward SALOMON, Inna SHCHERBAKOVA, Cecilia Giovanna Silvia COTTA-RAMUSINO, Jacob Rosenblum RUBENS, Robert James CITORIK, Zi Jun WANG
  • Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
    Patent number: 11692205
    Abstract: Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by cellular genomic or other sequences recognized by guide RNAs.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: July 4, 2023
    Assignee: EDITAS MEDICINE, INC.
    Inventors: Ari E. Friedland, Hariharan Jayaram, Barrett Ethan Steinberg
  • ENGINEERED CAS9 NUCLEASES
    Publication number: 20220177861
    Abstract: The present disclosure relates to Cas9 nuclease variants and methods of producing and using such variants.
    Type: Application
    Filed: July 14, 2021
    Publication date: June 9, 2022
    Inventors: Barrett Ethan Steinberg, Derek Cerchione
  • SYSTEMS AND METHODS FOR ONE-SHOT GUIDE RNA (ogRNA) TARGETING OF ENDOGENOUS AND SOURCE DNA
    Publication number: 20220017927
    Abstract: Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by cellular genomic or other sequences recognized by guide RNAs.
    Type: Application
    Filed: May 27, 2021
    Publication date: January 20, 2022
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Ari E. Friedland, Hariharan Jayaram, Barrett Ethan Steinberg