Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: The present invention provides delivery systems for positioning a gastrointestinal implant in a patient, for example, for treatment of a metabolic disease. Also provided are methods for assembling the delivery systems, methods of positioning a gastrointestinal implant, and methods of treatment of metabolic diseases, such as type 2 diabetes, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), obesity, and related comorbidities thereof.

Abstract: The present invention provides delivery systems for positioning a gastrointestinal implant in a patient, for example, for treatment of a metabolic disease. Also provided are methods for assembling the delivery systems, methods of positioning a gastrointestinal implant, and methods of treatment of metabolic diseases, such as type 2 diabetes, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), obesity, and related comorbidities thereof.

Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: The present invention provides delivery systems for positioning a gastrointestinal implant in a patient, for example, for treatment of a metabolic disease. Also provided are methods for assembling the delivery systems, methods of positioning a gastrointestinal implant, and methods of treatment of metabolic diseases, such as type 2 diabetes, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), obesity, and related comorbidities thereof.

Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.

Abstract: Gastrointestinal implants can be used to secure thin-walled sleeves, restrictor plates, and other devices within the gastrointestinal tract. An example implant includes three elements: a stomach anchor to resist distally oriented forces; a duodenal anchor to resist proximally oriented forces; and a connector element to keep the stomach anchor fixed relative to the stomach anchor. The implant is inserted into the gastrointestinal tract with a delivery device that holds the implant in a compressed state for minimally invasive delivery until the implant is positioned properly. Upon releasing from the delivery device, the implant expands to a relaxed state across the pylorus, allowing prongs that extending outward from the stomach and duodenal anchors to engage tissue in the gastrointestinal tract. The deployed implant may also include a thin-walled sleeve that extends into the intestine from the stomach anchor, duodenal anchor, or connector element.

Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: An endoscope hood device for moving a gastrointestinal implant device within a natural lumen of a gastrointestinal tract. The endoscope hood device comprises an atraumatic flared retrieval hood configured to attach to and fit over a distal end of an endoscope. The atraumatic flared retrieval hood comprises a length configured to cover a plurality of protrusions on a surface of the gastrointestinal implant device, the plurality of protrusions comprising both proximal facing protrusions and distal facing protrusions of the gastrointestinal implant device. The atraumatic flared retrieval hood comprises a diameter configured to fit within a human esophagus without damage to the esophagus, and comprises a material of a bend radius configured to move slidably against the esophagus without damage to the esophagus.

Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.

Abstract: Gastrointestinal implants can be used to secure thin-walled sleeves, restrictor plates, and other devices within the gastrointestinal tract. An example implant includes three elements: a stomach anchor to resist distally oriented forces; a duodenal anchor to resist proximally oriented forces; and a connector element to keep the stomach anchor fixed relative to the stomach anchor. The implant is inserted into the gastrointestinal tract with a delivery device that holds the implant in a compressed state for minimally invasive delivery until the implant is positioned properly. Upon releasing from the delivery device, the implant expands to a relaxed state across the pylorus, allowing prongs that extending outward from the stomach and duodenal anchors to engage tissue in the gastrointestinal tract. The deployed implant may also include a thin-walled sleeve that extends into the intestine from the stomach anchor, duodenal anchor, or connector element.

Abstract: A proximity sensor for a Laser Guided Bomb (LGB) is provided. A proximity sensor for a Laser Guided Bomb (LGB) includes: an electronics package unit (EPU) configured to be connected to a front end of a warhead; and at least one sensor separate from the EPU and configured to be connected to a forward adapter that is connected to the front end of the warhead. The at least one sensor is configured to obtain data that is used to determine a height above ground of the LGB. The EPU is configured to compare the determined height above ground to a predefined value. The EPU is configured to generate a detonation signal for the warhead based on the determined height above ground being equal to or less than the predefined value.

Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.

Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.

Abstract: An implant includes a collapsible anchor to be deployed within a lumen and a protrusion coupled to the anchor. The protrusion, in a constrained state, extends a distance from an exterior surface of the anchor and, in an unconstrained state, extends further from the exterior surface of the anchor. Also included is a biodegradable constraint, such as a biodegradable tube or suture, configured to maintain the protrusion in the constrained state until the constraint releases. The implant may include additional biodegradable constraints, each constraint configured to maintain the protrusion in a different constrained state and to degrade over a different predetermined period after the implant has been deployed within the lumen. The protrusion may include a bi-directional barb or an open loop. The protrusion may be configured to penetrate a wall of the lumen and to allow tissue to grow about the protrusion.

Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.

Abstract: A gastrointestinal implant device comprises a planar proximal element configured to reside in a stomach to resist distal migration, a distal element configured to reside in an intestine to resist proximal migration and one or more tethers coupling the planar proximal element to the distal element.

Abstract: An endoscope hood device for moving a gastrointestinal implant device within a natural lumen of a gastrointestinal tract. The endoscope hood device comprises an atraumatic flared retrieval hood configured to attach to and fit over a distal end of an endoscope. The atraumatic flared retrieval hood comprises a length configured to cover a plurality of protrusions on a surface of the gastrointestinal implant device, the plurality of protrusions comprising both proximal facing protrusions and distal facing protrusions of the gastrointestinal implant device. The atraumatic flared retrieval hood comprises a diameter configured to fit within a human esophagus without damage to the esophagus, and comprises a material of a bend radius configured to move slidably against the esophagus without damage to the esophagus.