Patents by Inventor Barry Bleske

Barry Bleske has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12653778
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Grant
    Filed: September 11, 2025
    Date of Patent: June 16, 2026
    Assignee: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Patent number: 12616807
    Abstract: Provided herein are dry powder formulations comprising at least one active pharmaceutical ingredient suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including respiratory conditions, hemodynamic collapse, seizures, migraines, and other conditions.
    Type: Grant
    Filed: May 20, 2024
    Date of Patent: May 5, 2026
    Assignee: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske
  • Publication number: 20260076897
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: November 26, 2025
    Publication date: March 19, 2026
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20260007594
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: September 11, 2025
    Publication date: January 8, 2026
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Patent number: 12414916
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Grant
    Filed: March 29, 2023
    Date of Patent: September 16, 2025
    Assignee: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20250000792
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: September 12, 2024
    Publication date: January 2, 2025
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Patent number: 12102629
    Abstract: Nasally targeted dry powder compositions and methods for their use in the treatment of exposure to organophosphate compounds including chemical warfare agents and pesticides. Compositions include anticholinergic agents and cholinesterase reactivator agents used for primary treatment and vasoactive agents and benzodiazepines used for secondary treatment of exposure, and combinations of these agents. Compositions incorporate excipients and enabling agents such as permeation enhancers, and optimal sizing of active pharmaceutical ingredient particle size to improve drug delivery across the nasal mucosa, stability, and resistance to heat degradation. Packaging and configuration of devices for dry powder nasal compositions enable their use by non-medical personnel in civilian mass casualty or battlefield environments.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: October 1, 2024
    Assignee: BELHAVEN BIOPHARMA, INC.
    Inventors: Barry Bleske, Ted William Lanpher
  • Patent number: 12097287
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Grant
    Filed: January 12, 2024
    Date of Patent: September 24, 2024
    Assignee: BELHAVEN BIOPHARMA INC.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20240299680
    Abstract: Provided herein are dry powder formulations comprising at least one active pharmaceutical ingredient suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including respiratory conditions, hemodynamic collapse, seizures, migraines, and other conditions.
    Type: Application
    Filed: May 20, 2024
    Publication date: September 12, 2024
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske
  • Patent number: 12005185
    Abstract: Provided herein are dry powder formulations comprising at least one active pharmaceutical ingredient suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including respiratory conditions, hemodynamic collapse, seizures, migraines, and other conditions.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: June 11, 2024
    Assignee: BELHAVEN BIOPHARMA INC.
    Inventors: Scott Lyman, Barry Bleske
  • Publication number: 20240148646
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: January 12, 2024
    Publication date: May 9, 2024
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Patent number: 11872308
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: January 16, 2024
    Assignee: BELHAVEN BIOPHARMA INC.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20230240983
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: March 29, 2023
    Publication date: August 3, 2023
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20230233460
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: March 30, 2023
    Publication date: July 27, 2023
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20230191047
    Abstract: Provided herein are dry powder formulations comprising at least one active pharmaceutical ingredient suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including respiratory conditions, hemodynamic collapse, seizures, migraines, and other conditions.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 22, 2023
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske
  • Patent number: 11617716
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: April 4, 2023
    Assignee: BELHAVEN BIOPHARMA INC.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Publication number: 20220395457
    Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
    Type: Application
    Filed: June 9, 2022
    Publication date: December 15, 2022
    Applicant: Belhaven BioPharma Inc.
    Inventors: Scott Lyman, Barry Bleske, Ted William Lanpher
  • Patent number: 11433063
    Abstract: Nasally targeted dry powder compositions and methods for their use in the treatment of exposure to organophosphate compounds including chemical warfare agents and pesticides. Compositions include anticholinergic agents and cholinesterase reactivator agents used for primary treatment and vasoactive agents and benzodiazepines used for secondary treatment of exposure, and combinations of these agents. Compositions incorporate excipients and enabling agents such as permeation enhancers, and optimal sizing of active pharmaceutical ingredient particle size to improve drug delivery across the nasal mucosa, stability, and resistance to heat degradation. Packaging and configuration of devices for dry powder nasal compositions enable their use by non-medical personnel in civilian mass casualty or battlefield environments.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: September 6, 2022
    Assignee: BELHAVEN BIOPHARMA, INC.
    Inventors: Barry Bleske, Ted William Lanpher