Patents by Inventor Barry Bunin

Barry Bunin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8195409
    Abstract: A portable threat detection apparatus and method is disclosed which may comprise a plurality of acoustic emission sensors arranged in a cluster, forming a polygon defining at least two axes of alignment between respective pairs of acoustic emission sensors; a computing device in cooperation with a non-transitory computer readable storage medium comprising computer readable instructions for performing: receiving a first signal produced by a first acoustic emission sensor within a respective pair of acoustic emission sensors, in response to the first acoustic emission sensor detecting an acoustic emission from a source, and receiving a second signal produced by a second acoustic emission sensor within the respective pair of acoustic emission sensors, in response to the second acoustic emission sensor detecting the acoustic emission; determining a cross-correlation factor between the first signal and the second signal; and, determining a bearing to the source based on the cross correlation factor.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: June 5, 2012
    Assignee: The Trustees of the Stevens Institute of Technology
    Inventors: Michael Bruno, Barry Bunin, Laurent Fillinger, Howard Goheen, Alexander Sedunov, Nikolay Sedunov, Alexander Sutin, Mikhail Tsionskiy, Jeremy Turner, Malcolm Kahn, Hady R. Salloum
  • Publication number: 20110144930
    Abstract: A portable threat detection apparatus and method is disclosed which may comprise a plurality of acoustic emission sensors arranged in a cluster, forming a polygon defining at least two axes of alignment between respective pairs of acoustic emission sensors; a computing device in cooperation with a non-transitory computer readable storage medium comprising computer readable instructions for performing: receiving a first signal produced by a first acoustic emission sensor within a respective pair of acoustic emission sensors, in response to the first acoustic emission sensor detecting an acoustic emission from a source, and receiving a second signal produced by a second acoustic emission sensor within the respective pair of acoustic emission sensors, in response to the second acoustic emission sensor detecting the acoustic emission; determining a cross-correlation factor between the first signal and the second signal; and, determining a bearing to the source based on the cross correlation factor.
    Type: Application
    Filed: November 3, 2010
    Publication date: June 16, 2011
    Inventors: Michael Bruno, Barry Bunin, Laurent Fillinger, Howard Goheen, Alexander Sedunov, Nikolay Sedunov, Alexander Sutin, Mikhail Tsionskiy, Jeremy Turner, Malcolm Kahn
  • Publication number: 20080090785
    Abstract: Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsinlike activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.
    Type: Application
    Filed: May 9, 2005
    Publication date: April 17, 2008
    Applicant: Proteolix, Inc.
    Inventors: Mark Smyth, Guy Laidig, Ronald Borchardt, Barry Bunin, Craig Crews, John Musser, Kevin Shenk, Peggy Radel
  • Publication number: 20070191284
    Abstract: Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.
    Type: Application
    Filed: April 11, 2007
    Publication date: August 16, 2007
    Applicant: Proteolix, Inc.
    Inventors: Mark Smyth, Guy Laidig, Ronald Borchardt, Barry Bunin, Craig Crews, John Musser
  • Publication number: 20070015755
    Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
    Type: Application
    Filed: September 20, 2006
    Publication date: January 18, 2007
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: Clifford Bryant, Barry Bunin, Erica Kraynack, John Patterson
  • Publication number: 20050245435
    Abstract: Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.
    Type: Application
    Filed: April 14, 2005
    Publication date: November 3, 2005
    Applicant: Proteolix, Inc.
    Inventors: Mark Smyth, Guy Laidig, Ronald Borchardt, Barry Bunin, Craig Crews, John Musser, John Schneekloth, John Chabala