Abstract: Tools and techniques for providing joint position error test system are provided. A system includes a head sensing unit coupled to a joint position error processor. The head sensing unit may include a positional sensor and further be configured to be coupled to the head of a test subject. The joint position error processor may include a processor, and non-transitory computer readable media comprising instructions executable by the processor to record reference sensor data from the positional sensor when the test subject's head is in a reference position, record return sensor data when the test subject's head is in a return position. The instructions may further be executable to determine a position error based on the reference sensor data and the return sensor data, and to further determine the presence of a condition of the test subject based on the position error.

Abstract: Tools and techniques for providing joint position error test system are provided. A system includes a head sensing unit coupled to a joint position error processor. The head sensing unit may include a positional sensor and further be configured to be coupled to the head of a test subject. The joint position error processor may include a processor, and non-transitory computer readable media comprising instructions executable by the processor to record reference sensor data from the positional sensor when the test subject's head is in a reference position, record return sensor data when the test subject's head is in a return position. The instructions may further be executable to determine a position error based on the reference sensor data and the return sensor data, and to further determine the presence of a condition of the test subject based on the position error.

Abstract: Tools and techniques for providing joint position error test system are provided. A system includes a head sensing unit coupled to a joint position error processor. The head sensing unit may include a positional sensor and further be configured to be coupled to the head of a test subject. The joint position error processor may include a processor, and non-transitory computer readable media comprising instructions executable by the processor to record reference sensor data from the positional sensor when the test subject's head is in a reference position, record return sensor data when the test subject's head is in a return position. The instructions may further be executable to determine a position error based on the reference sensor data and the return sensor data, and to further determine the presence of a condition of the test subject based on the position error.

Abstract: The invention provides methods for inhibiting psychostimulant-induced or nicotine-induced craving of additional psychostimulants (e.g., cocaine or amphetamine) or nicotine. In these methods, D1-like antagonists or D1-like agonists are administered to a patient dependent on psychostimulant drugs or nicotine and therefore susceptible to, or suffering from, such a craving. Also disclosed is an animal model system useful for measuring the ability of test compounds to inhibit psychostimulant-induced or nicotine-induced cravings in humans.

Abstract: The invention provides methods for inhibiting psychostimulant-induced or nicotine-induced craving of additional psychostimulants (e.g., cocaine or amphetamine) or nicotine. In these methods, D1-like antagonists or D1-like agonists are administered to a patient dependent on psychostimulant drugs or nicotine and therefore susceptible to, or suffering from, such a craving. Also disclosed is an animal model system useful for measuring the ability of test compounds to inhibit pyschostimulant-induced or nicotine-induced cravings in humans.